Massachusetts Institute of Technology researchers have devised a novel cancer treatment that destroys tumor cells by first disarming their defenses, then hitting them with a lethal dose of DNA damage. In studies with mice, the research team showed that this one-two punch, which relies on a nanoparticle that carries two drugs and releases them at different times, dramatically shrinks lung and breast tumors.
When sunlight shines on today’s solar cells, much of the incoming energy is given off as waste heat rather than electrical current. In a few materials, however, extra energy produces extra electrons—behavior that could significantly increase solar-cell efficiency. A team has now identified the mechanism by which that phenomenon happens, yielding new design guidelines for using those special materials to make high-efficiency solar cells.
Terahertz imaging, which is already familiar from airport security checkpoints, has a number of other promising applications. Like sonar or radar, terahertz imaging produces an image by comparing measurements across an array of sensors. Those arrays have to be very dense, since the distance between sensors is proportional to wavelength.
Launched in 2013, the national BRAIN Initiative aims to revolutionize our understanding of cognition by mapping the activity of every neuron in the human brain, revealing how brain circuits interact to create memories, learn new skills and interpret the world around us. Before that can happen, neuroscientists need new tools that will let them probe the brain more deeply and in greater detail.
Out on the edge of the universe, 75,000 light-years from us, a galaxy known as Segue 1 has some unusual properties: It’s the faintest galaxy ever detected. It’s very small, containing only about 1,000 stars. And it has a rare chemical composition, with vanishingly small amounts of metallic elements present.
Materials that can be used for thermoelectric devices have been known for decades. But, until now, there has been no good explanation for why just a few materials work well for these applications, while most others do not. Now researchers say they have finally found a theoretical explanation for the differences, which could lead to the discovery of new, improved thermoelectric materials.
Researchers around the world have been working to harness the unusual properties of graphene, a 2-D sheet of carbon atoms. But graphene lacks one important characteristic that would make it even more useful: a property called a bandgap, which is essential for making devices such as computer chips and solar cells.
Starting in 2018, researchers at Massachusetts Institute of Technology will have access to a new building dedicated to nanoscale research at the heart of the Cambridge campus. The 200,000-ft2 building, called “MIT.nano,” will be built at the heart of the Cambridge campus and will house cleanroom, imaging and prototyping facilites. An estimated 2,000 MIT researchers may ultimately make use of the building.
In formulating policies to address greenhouse gas emissions, or evaluating the potential impact of different energy technologies on global climate change, one of the thorniest issues is how to account for the very distinctive characteristics of various different gases. Methane is a potent greenhouse gas, as well as a significant byproduct of using natural gas. But a direct comparison between methane and carbon dioxide is complicated.
The smallest, most abundant marine microbe, Prochlorococcus, is a photosynthetic bacteria species essential to the marine ecosystem. An estimated billion upon billion of the single-cell creatures live in the oceans, forming the base of the marine food chain and occupying a range of ecological niches based on temperature, light and chemical preferences, and interactions with other species.
Our DNA is under constant attack from many sources. Fortunately, cells have several major DNA repair systems that can fix this damage, which may lead to diseases if not mended. A team of researchers has developed a test that can rapidly assess several DNA repair systems, which could help determine individuals’ risk of developing cancer and help doctors predict how a given patient will respond to chemotherapy drugs.
Unlike healthy cells, cancer cells thrive when deprived of oxygen. Tumors in low-oxygen environments tend to be more resistant to therapy and spread more aggressively to other parts of the body. Measuring tumors’ oxygen levels could help doctors make decisions about treatments, but there’s currently no way to make such measurements. However, a new sensor developed at Massachusetts Institute of Technology could change that.
These days, Hugh Herr, an assoc. prof. of media arts and sciences at Massachusetts Institute of Technology, gets about 100 emails daily from people across the world interested in his bionic limbs. Messages pour in from amputees seeking prostheses and from media outlets pursuing interviews. Then there are students looking to join Herr’s research group.
When an earthquake and tsunami struck the Fukushima Daiichi nuclear plant complex in 2011, neither the quake nor the inundation caused the ensuing contamination. Rather, it was the aftereffects—specifically, the lack of cooling for the reactor cores, due to a shutdown of all power at the station—that caused most of the harm. A new design for nuclear plants built on floating platforms could help avoid such consequences in the future.
A quasiparticle called an exciton has been understood theoretically for decades. But exciton movement within materials has never been directly observed. Now scientists have achieved that feat, imaging excitons’ motions directly. This could enable research leading to significant advances in electronics, they say, as well as a better understanding of natural energy-transfer processes, such as photosynthesis.
Since the discovery of the Antarctic ozone hole, scientists, policymakers and the public have wondered whether we might someday see a similarly extreme depletion of ozone over the Arctic. But a new Massachusetts Institute of Technology study finds some cause for optimism: Ozone levels in the Arctic haven’t yet sunk to the extreme lows seen in Antarctica, because international efforts to limit ozone-depleting chemicals have been successful.
Delivering chemotherapy drugs in nanoparticle form could help reduce side effects by targeting the drugs directly to the tumors. In recent years, scientists have developed nanoparticles that deliver one or two chemotherapy drugs, but it has been difficult to design particles that can carry any more than that in a precise ratio. Now Massachusetts Institute of Technology chemists have devised a new way to build such nanoparticles.
It’s an obvious truism, but one that may soon be outdated: The problem with solar power is that sometimes the sun doesn’t shine. Now a team at Massachusetts Institute of Technology and Harvard Univ. has come up with an ingenious workaround: a material that can absorb the sun’s heat and store that energy in chemical form, ready to be released again on demand.
Picking out a face in the crowd is a complicated task: Your brain has to retrieve the memory of the face you’re seeking, then hold it in place while scanning the crowd, paying special attention to finding a match. A new study reveals how the brain achieves this type of focused attention on faces or other objects.
Thousands of consumer products contain nanoparticles added by manufacturers to improve texture, kill microbes or enhance shelf life, among other purposes. However, several studies have shown that some of these engineered nanoparticles can be toxic to cells. A new study from Massachusetts Institute of Technology and the Harvard School of Public Health suggests that certain nanoparticles can also harm DNA.
Using a laser to place individual rubidium atoms near the surface of a lattice of light, scientists at Massachusetts Institute of Technology and Harvard Univ. have developed a new method for connecting particles—one that could help in the development of powerful quantum computing systems.
The next time you feel a sneeze coming on, raise your elbow to cover up that multiphase turbulent buoyant cloud you’re about to expel. That’s right: A novel study by Massachusetts Institute of Technology researchers shows that coughs and sneezes have associated gas clouds that keep their potentially infectious droplets aloft over much greater distances than previously realized.
Researchers are working on a new algorithm that could make re-identification much easier for computers by identifying the major orientations in 3-D scenes. The same algorithm could also simplify the problem of scene understanding, one of the central challenges in computer vision research.
Economics has a “law of one price,” which states that identical goods should, in theory, sell for identical prices or else markets will even out the differences. Empirical work on the topic, however, has produced little evidence in support of this “law”. Now, a newly published paper presents evidence of a strong convergence of prices within the Eurozone, the region of European countries sharing a common currency.
Fossil remains show that sometime around 252 million years ago, about 90% of all species on Earth were suddenly wiped out in what was the largest of this planet’s five known mass extinctions. But pinpointing the culprit has been difficult, and controversial. Now, a team of Massachusetts Institute of Technology researchers may have found enough evidence to convict the guilty parties, but you’ll need a microscope to see the killers.