Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer. However, the particles have to be injected into patients, which has limited their usefulness so far. Now, researchers have developed a new type of nanoparticle that can be delivered orally and absorbed through the digestive tract, allowing patients to simply take a pill instead of receiving injections.
Lidar rangefinders gauge depth by emitting short bursts of laser light and measuring the time it takes for reflected photons to arrive back and be detected. In Science, researchers from Massachusetts Institute of Technology’s Research Laboratory of Electronics describe a new lidar-like system that can gauge depth when only a single photon is detected from each location.
A $500 “nanocamera” that can operate at the speed of light has been developed by researchers in the Massachusetts Institute of Technology Media Lab. The 3-D camera could be used in medical imaging and collision-avoidance detectors for cars, and to improve the accuracy of motion tracking and gesture-recognition devices used in interactive gaming.
Rain as acidic as undiluted lemon juice may have played a part in killing off plants and organisms around the world during the most severe mass extinction in Earth’s history. About 252 million years ago, the end of the Permian period brought about a worldwide collapse known as the Great Dying, during which a vast majority of species went extinct. The cause of such a massive extinction is a matter of scientific debate.
Massachusetts Institute of Technology chemical engineers have developed a novel way to generate nanoparticles that can recognize specific molecules, opening up a new approach to building durable sensors for many different compounds, among other applications. To create these “synthetic antibodies,” the researchers used carbon nanotubes.
After working at a software company for four years, Massachusetts Institute of Technology (MIT) alumnus Andrew Dougherty was itching to do something entrepreneurial in the energy industry. Browsing the Website of MIT’s $50K (now $100K) Entrepreneurship Competition, he found an exact match for his interests: an invention by MIT postdoctoral researcher Javier García-Martínez that used nanotechnology to improve the efficiency of oil refining.
Those who study hydrophobic materials are familiar with a theoretical limit on the time it takes for a water droplet to bounce away from such a surface. But Massachusetts Institute of Technology researchers have now found a way to burst through that perceived barrier, reducing the contact time by at least 40%.
The “firefighting trap” is a term often used by business managers to describe a shortsighted cycle of problem-solving: dealing with “fires,” or problems, as they arise, but failing to address the underlying cause, thereby increasing the chance that the same problem will reoccur in the future. Massachusetts Institute of Technology has looked at the original inspiration for this “quick-fix” management strategy: firefighting itself.
Cooling systems generally rely on water pumped through pipes to remove unwanted heat. Now, researchers at Massachusetts Institute of Technology and in Australia have found a way of enhancing heat transfer in such systems by using magnetic fields, a method that could prevent hotspots that can lead to system failures. The system could also be applied to cooling everything from electronic devices to advanced fusion reactors, they say.
For nearly as long as astronomers have been able to observe asteroids, a question has gone unanswered: Why do the surfaces of most asteroids appear redder than meteorites—the remnants of asteroids that have crashed to Earth? Scientists have now found that Mars, not Earth, shakes up some near-Earth asteroids.
In deciding how best to meet the world’s growing needs for energy, the answers depend crucially on how the question is framed. Looking for the most cost-effective path provides one set of answers; including the need to curtail greenhouse gas emissions gives a different picture. Adding the need to address looming shortages of fresh water, it turns out, leads to a very different set of choices.
About half of all cancer patients have a mutation in a gene called p53, which allows tumors to survive and continue growing even after chemotherapy severely damages their DNA. A new study from Massachusetts Institute of Technology biologists has found that tumor cells with mutated p53 can be made much more vulnerable to chemotherapy by blocking another gene called MK2.
Much artificial intelligence research is concerned with finding statistical correlations between variables. As the number of variables grows, calculating their aggregate statistics becomes dauntingly complex. But that calculation can be drastically simplified if you know something about the structure of the data.
Lithium-air batteries have become a hot research area in recent years: They hold the promise of drastically increasing power per battery weight, which could lead, for example, to electric cars with a much greater driving range. But bringing that promise to reality has faced a number of challenges.
When an earthquake and tsunami struck Japan’s Fukushima nuclear power plant in 2011, crews sprayed cooling seawater on the reactors, but to no avail. One possible reason: Droplets can’t land on surfaces that hot and instantly begin to evaporate, forming a thin layer of vapor and then bouncing along it. Now, MIT researchers have come up with a way to cool hot surfaces more effectively by keeping droplets from bouncing.
Researchers find that huge craters on the near side of the moon may overstate the intensity of asteroid impacts about 4.1 billion years ago.
Many efforts to smooth out the variability of renewable energy sources have focused on batteries, which could fill gaps lasting hours or days. But Massachusetts Institute of Technology’s Charles Forsberg has come up with a much more ambitious idea: He proposes marrying a nuclear power plant with another energy system, which he argues could add up to much more than the sum of its parts.
As transistors get smaller, they also become less reliable. So far, computer-chip designers have been able to work around that problem, but in the future, it could mean that computers stop improving at the rate we’ve come to expect. A third possibility, which some researchers have begun to float, is that we could simply let our computers make more mistakes.
Nitric oxide (NO) is one of the most important signaling molecules in living cells, carrying messages within the brain and coordinating immune system functions. In many cancerous cells, levels are perturbed, but very little is known about how NO behaves in both healthy and cancerous cells. Until now.
Cisplatin is a chemotherapy drug given to more than half of all cancer patients. The drug kills cells very effectively by damaging nuclear DNA, but if tumors become resistant to cisplatin they often grow back. A new study offers a possible way to overcome that resistance. The researchers found that when cisplatin was delivered to cellular structures called mitochondria, DNA in this organelle was damaged, leading to cancer cell death.
In August, Massachusetts Institute of Technology researchers identified an exoplanet with an extremely brief orbital period: The team found that Kepler 78b, a small, intensely hot planet 400 light-years from Earth, circles its star in just 8.5 hrs. Now this same team has found that Kepler 78b shares another characteristic with Earth: its mass.
Dark matter, believed by physicists to outweigh all the normal matter in the universe by more than five to one, is by definition invisible. But certain features associated with dark matter might be detectable, according to some of the many competing theories describing this elusive matter. Now scientists have developed a tool that could test some of these predictions and thus prove, or disprove, one of the leading theories.
Researchers at Massachusetts Institute of Technology have succeeded in producing and measuring a coupling of photons and electrons on the surface of an unusual type of material called a topological insulator. This type of coupling had been predicted by theorists, but never observed.
An aggressive form of breast cancer known as “triple negative” is very difficult to treat: Chemotherapy can shrink such tumors for a while, but in many patients they grow back and gain resistance to the original drugs. To overcome that resistance, chemical engineers have designed nanoparticles that carry the cancer drug doxorubicin, as well as short strands of RNA that can shut off one of the genes that cancer cells use to escape the drug.
A central topic in spoken-language-systems research is what’s called speaker diarization, or computationally determining how many speakers feature in a recording and which of them speaks when. Speaker diarization would be an essential function of any program that automatically annotated audio or video recordings.