The latest version of a microfluidic device for capturing rare circulating tumor cells is the first designed specifically to capture clusters of two or more cells, rather than single cells. The new device, called the Cluster-Chip, was developed by the same Massachusetts General Hospital (MGH) research team that created previous microchip-based devices.
Quantum computers are in theory capable of simulating the interactions of molecules at a level...
Using a smart tablet and a red beam of light, Georgia Institute of Technology researchers have...
Quantum computers are in theory capable of simulating the interactions of molecules at a level...
Researchers from the Georgia Institute of Technology have developed a novel cellular sensing platform that promises to expand the use of semiconductor technology in the development of next-generation bioscience and biotech applications. The research proposes and demonstrates the world’s first multi-modality cellular sensor arranged in a standard low-cost CMOS process.
Scientists have determined the 3-D structure of a key part of a protein that is associated with glaucoma and identified regions of this domain that correlate with severe forms of the disease. The new crystal structure is of the olfactomedin (OLF) domain in myocilin, a protein implicated in glaucoma. Many proteins have OLF domains, but mutations in the OLF domain of myocilin are linked to early-onset glaucoma.
A first-of-its-kind robotic vehicle recently dove to depths never before visited under Antarctica’s Ross Ice Shelf and brought back video of life on the seafloor. A team of scientists and engineers from the Georgia Institute of Technology assembled the unmanned, underwater vehicle on Antarctica. They deployed (and retrieved) the vehicle through a 12-in diameter hole through 20 m of ice and another 500 m of water to the sea floor.
Researchers have developed a novel technique for crafting nanometer-scale necklaces based on tiny star-like structures threaded onto a polymeric backbone. The technique could provide a new way to produce hybrid organic-inorganic shish kebab structures from semiconducting, magnetic, ferroelectric and other materials that may afford useful nanoscale properties.
Researchers at Carnegie Mellon Univ. (CMU) who develop snake-like robots have picked up a few tricks from real sidewinder rattlesnakes on how to make rapid and even sharp turns with their undulating, modular device. Working with colleagues at the Georgia Institute of Technology and Zoo Atlanta, they have analyzed the motions of sidewinders and tested their observations on CMU’s snake robots.
To fully understand how nanomaterials behave, one must also understand the atomic-scale deformation mechanisms that determine their structure and, therefore, their strength and function. Researchers have engineered a new way to observe and study these mechanisms and, in doing so, have revealed an interesting phenomenon in a well-known material, tungsten.
It started with a trip to the basement of the American Museum of Natural History in New York to inspect preserved animal hides. Later, Georgia Institute of Technology researchers built a wind tunnel about 2 ft tall, complete with a makeshift eye. By putting both steps together, the team discovered that 22 species of mammals are the same: their eyelash length is one-third the width of their eye.
A new study has found that La Niña-like conditions in the Pacific Ocean off the coast of Panamá were closely associated with an abrupt shutdown in coral reef growth that lasted 2,500 years. The study suggests that future changes in climate similar to those in the study could cause coral reefs to collapse in the future.
When oil from the Deepwater Horizon spill first began washing ashore on Pensacola Municipal Beach in June 2010, populations of sensitive microorganisms, including those that capture sunlight or fix nitrogen from the air, began to decline. At the same time, organisms able to digest light components of the oil began to multiply, starting the process of converting the pollutant to carbon dioxide and biomass.
Artists, print designers and interior decorators have long had access to a broad palette of paint and ink colors for their work. Now, researchers have created a broad color palette of electrochromic polymers, materials that can be used for sunglasses, window tinting and other applications that rely on electrical current to produce color changes.
Ribonucleotides, units of RNA, can become embedded in genomic DNA during processes such as DNA replication and repair, affecting the stability of the genome by contributing to DNA fragility and mutability. Scientists have known about the presence of ribonucleotides in DNA, but until now had not been able to determine exactly what they are and where they are located in the DNA sequences.
For swimming through sand, a slick and slender snake can perform better than a short and stubby lizard. That’s one conclusion from a study of the movement patterns of the shovel-nosed snake, a native of the Mojave Desert of the southwest U.S.
If you’re sitting in a coffee shop, tapping away on your laptop, feeling safe from hackers because you didn’t connect to the shop’s Wi-Fi, think again. The bad guys may be able to see what you’re doing just by analyzing the low-power electronic signals your laptop emits even when it’s not connected to the Internet. And smartphones may be even more vulnerable to such spying.
Crowd science is making possible research projects that might otherwise be out of reach, tapping thousands of volunteers to help with such tasks as classifying animal photos, studying astronomical images, counting sea stars and examining cancer cell images. Also known as “citizen science,” these efforts to involve ordinary people in research projects have attracted interest from policy makers, scientific agencies and others.
More than 90% of cancer-related deaths are caused by the spread of cancer cells from their primary tumor site to other areas of the body. A new study has identified how one important gene helps cancer cells break free from the primary tumor.
A species of small fish uses a homemade coral-scented cologne to hide from predators, a new study has shown, providing the first evidence of chemical camouflage from diet in fish. Filefish evade predators by feeding on their home corals and emitting an odor that makes them invisible to the noses of predators, the study found.
Bathymetric lidars are used today primarily to map coastal waters. At nearly 600 lbs, the systems are large and heavy, and they require costly, piloted aircraft to carry them. A team at the Georgia Tech Research Institute has designed a new approach that could lead to bathymetric lidars that are much smaller and more efficient than the current full-size systems.
Microbes of interest to clinicians and environmental scientists rarely exist in isolation. Organisms essential to breaking down pollutants or causing illness live in complex communities, and separating one microbe from hundreds of companion species can be challenging for researchers seeking to understand environmental issues or disease processes.
Needles almost too small to be seen with the unaided eye could be the basis for new treatment options for two of the world’s leading eye diseases: glaucoma and corneal neovascularization. The microneedles, ranging in length from 400 to 700 microns, could provide a new way to deliver drugs to specific areas within the eye relevant to these diseases.
Today, petabytes of digital information are generated daily by such sources as social media, Internet activity, surveillance sensors and advanced research instruments. The results are often referred to as “big data”—accumulations so huge that highly sophisticated computer techniques are required to identify useful information hidden within. Graph analysis is a prime tool for finding the needle in the data haystack.
The AN/AAR-57 Common Missile Warning System (CMWS) helps protect Army aircraft from attack by shoulder-launched missiles and other threats. To keep this defensive system operating at maximum effectiveness, the Army periodically updates the software on the more than 1,000 AN/AAR-57 units in use around the world.
Plant scientists are working to improve important food crops to meet the food needs of a growing world population. However, boosting crop output will require improving more than what can be seen of these plants above the ground. Root systems are essential to gathering water and nutrients, but understanding what’s happening in these unseen parts of the plants has until now depended mostly on lab studies and subjective field measurements.
The amazing ability of sidewinder snakes to quickly climb sandy slopes was once something biologists only vaguely understood and roboticists only dreamed of replicating. By studying the snakes in a unique bed of inclined sand and using a snake-like robot to test ideas spawned by observing the real animals, both biologists and roboticists have now gained long-sought insights, including how sidewinders effectively traverse sandy slopes.
Anyone who has blown a bubble and seen how quickly it pops has first-hand experience on the major challenge in creating stable foams. At its most basic level, foam is a bunch of bubbles squished together. Liquid foams, a state of matter that arises from tiny gas bubbles dispersed in a liquid, are familiar in everyday life, from beer to bathwater. They also are important in commercial products and processes.
A team of Georgia Institute of Technology researchers has created speech-to-text software for Google Glass that helps hard-of-hearing users with everyday conversations. A hard-of-hearing person wears Glass while a second person speaks directly into a smartphone. The speech is converted to text, sent to Glass and displayed on its heads-up display.
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