Cartilage is notoriously difficult to repair or grow, but researchers at Duke Medicine have taken a step toward understanding how to regenerate the connective tissue. By adding a chemical to cartilage cells, the chemical signals spurred new cartilage growth, mimicking the effects of physical activity. The findings point to an ion channel called TRPV4 as a potential target for new therapies to treat osteoarthritis or even regrow cartilage.
Duke Univ. scientists have taken aim at what may be an Achilles' heel of the HIV virus....
Inventor Nikola Tesla imagined the technology to transmit energy through thin air almost a...
Much of the naturally occurring radioactivity in fracking wastewater might be removed by...
In the search for cheaper materials that mimic their purer, more expensive counterparts, researchers are abandoning hunches and intuition for theoretical models and pure computing power. In a new study, researchers from Duke Univ.’s Pratt School of Engineering used computational methods to identify dozens of platinum-group alloys that were previously unknown to science but could prove beneficial in a wide range of applications.
A Duke Univ. research team has developed a better recipe for synthetic replacement cartilage in joints. Combining two innovative technologies, the team found a way to create artificial replacement tissue that mimics both the strength and suppleness of native cartilage. Articular cartilage is the tissue on the ends of bones where they meet at joints in the body.
Converting solar energy into storable fuel remains one of the greatest challenges of modern chemistry. Chemists have commonly tried to use indium tin oxide (ITO) because it has transparency, but it also expensive and rare. Researchers at Duke Univ. has created something they hope can replace ITO: copper nanowires fused in a see-through film.
A team of scientists has created an artificial protein coupled with a sugar molecule that mimics a key site on the outer coat of HIV where antibodies can bind to neutralize a wide variety of HIV strains. The finding provides a potential new strategy in vaccine development to elicit the broadly neutralizing antibodies considered essential for long-lasting protection from the ever-changing HIV virus.
Human fingertips have several types of sensory neurons that are responsible for relaying touch signals to the central nervous system. Scientists have long believed these neurons followed a linear path to the brain with a "labeled-lines" structure. But new research on mouse whiskers reveals a surprise: At the fine scale, the sensory system's wiring diagram doesn't have a set pattern.
You might not think to look to a urine test to diagnose an eye disease. But a new Duke Univ. study says it can link what is in a patient's urine to gene mutations that cause retinitis pigmentosa, or RP, an inherited, degenerative disease that results in severe vision impairment and often blindness.
Working with a synthetic gene circuit designed to coax bacteria to grow in a predictable ring pattern, Duke Univ. scientists have revealed an underappreciated contributor to natural pattern formation: time. A series of experiments published by the Duke team show that their engineered gene circuit functions as a timing mechanism, triggering a predictable ring growth pattern that adjusts to the size of its environment.
According to a recent study led by scientists at Duke Univ., elevated levels of radioactivity, salts and metals have been found in river water and sediments at a site where treated water from oil and gas operations is discharged into a western Pennsylvania creek.
Coal-powered synthetic natural gas plants being planned in China would produce seven times more greenhouse gas emissions than conventional natural gas plants, and use up to 100 times the water as shale gas production, according to a new study by Duke Univ. researchers. These environmental costs have been largely neglected in the drive to meet the nation’s growing energy needs, the researchers say.
Electronic devices with touchscreens rely on transparent conductors made of indium tin oxide, or ITO. But cost and the physical limitations of this material are limiting progress in developing flexible touchscreens. A research collaboration between the Univ. of Pennsylvania and Duke Univ. is exploring the use of nanowires to replace ITO, and are using simulation tools to determine how they might work.
Microscopic tears in a new kind of man-made material may actually help the substance bulk up like a bodybuilder at the gym. A Duke Univ. team has shown how normally destructive mechanical forces can be channeled to bring about stronger materials. The material responses are like Silly Putty transforming into a solid as stiff as a pen cap or a runny liquid transforming into soft Jell-O.
Duke Univ. biomedical engineers and genome researchers have developed a proof-of-principle approach using light to detect infections before patients show symptoms. The approach was demonstrated in human samples, and researchers are now developing the technique for placement on a chip, which could provide fast, simple and reliable information about a patient. A diagnostic device based on this chip also could be made portable.
Hours spent at the video gaming console not only train a player's hands to work the buttons on the controller, they probably also train the brain to make better and faster use of visual input, according to Duke Univ. researchers.
Duke University engineers have developed a novel method for producing clean hydrogen, which could prove essential to weaning society off of fossil fuels and their environmental implications. The Duke engineers, using a new catalytic approach, have shown in the laboratory that they can reduce carbon monoxide levels to nearly zero in the presence of hydrogen and the harmless byproducts of carbon dioxide and water.
Scientists sampling 127 shallow drinking water wells in areas overlying Fayetteville Shale gas production in north-central Arkansas found no evidence of groundwater contamination. The team of scientists at Duke University and the U.S. Geological Survey (USGS) analyzed the samples for major and trace elements and hydrocarbons, and used isotopic tracers to identify the sources of possible contaminants.
Duke University biomedical engineers have grown 3D human heart muscle that acts just like natural tissue. This advancement could be important in serving as a platform for testing new heart disease medicines. The “heart patch” grown in the laboratory from human cells overcomes two major obstacles facing cell-based therapies—the patch conducts electricity at about the same speed as natural heart cells and it “squeezes” appropriately.
Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. The "heart patch" grown in the laboratory from human cells overcomes two major obstacles facing cell-based therapies—the patch conducts electricity at about the same speed as natural heart cells and it "squeezes" appropriately.
Seven years ago, Duke University engineers demonstrated the first working invisibility cloak in complex laboratory experiments. Now it appears creating a simple cloak has become a lot simpler through 3D printing. Producing a cloak through this method is inexpensive and easy; and the small one the team made looks like a Frisbee disc made out of Swiss cheese.
A 3D image of a protein that serves as an on-off switch as it binds to receptors on the surface of a cell suggests there may be a sort of main power switch that could be tripped. These surface receptors are responsible for helping cells discern light, set the heart racing, or detect pain. The finding could help in the development of more effective drugs to switch on or off the cell receptors that regulate bodily functions.
Observing the evolution of a particular type of antibody in an infected HIV-1 patient has provided insights that will enable vaccination strategies that mimic the actual antibody development within the body. Spearheaded by Duke University, the multi-institution study included analysis from Los Alamos National Laboratory and used high-energy X-rays from the Advanced Photon Source at Argonne National Laboratory.
Tougher EPA air-quality standards could spur an increased shift away from coal and toward natural gas for electricity generation, according to a new Duke University study. Complying with stricter regulations on sulfur dioxide, particulate matter, nitrogen oxide, and mercury may make nearly two-thirds of the nation's coal-fired power plants as expensive to run as plants powered by natural gas. The regulations would make 65% of U.S. coal plants as expensive as natural gas, even if gas prices rise significantly.
By reproducing in the laboratory the complex interactions that cause human genes to turn on inside cells, Duke University bioengineers have created a system they believe can benefit gene therapy research and the burgeoning field of synthetic biology. This new approach should help basic scientists as they tease out the effects of "turning on" or "turning off" many different genes, as well as clinicians seeking to develop new gene-based therapies for human disease.
Hydraulically fractured natural gas wells are producing less wastewater per unit of gas recovered than conventional wells would. But the scale of fracking operations in the Marcellus shale region is so vast that the wastewater it produces threatens to overwhelm the region's wastewater disposal capacity, according to new analysis by researchers at Duke and Kent State universities.
Just as horses shake off pesky flies by twitching their skin, ships may soon be able to shed the unwanted accumulation of bacteria and other marine growth with the flick of a switch. Duke University engineers have developed a material that can be applied like paint to the hull of a ship and will literally be able to dislodge bacteria, keeping it from accumulating on the ship's surface.
Duke University engineers are layering atom-thick lattices of carbon with polymers to create unique materials with a broad range of applications, including artificial muscles. The lattice, known as graphene, is made of pure carbon and appears under magnification like chicken wire. Because of its unique optical, electrical, and mechanical properties, graphene is used in electronics, energy storage, composite materials, and biomedicine.
- Page 1