Scientists at The Scripps Research Institute (TSRI) have discovered how one gene is essential to hearing, uncovering a cause of deafness and suggesting new avenues for therapies. The new study, published in Neuron, shows how mutations in a gene called Tmie can cause deafness from birth. Underlining the critical nature of their findings, researchers were able to reintroduce the gene in mice and restore the process underpinning hearing.
In a study that identifies a new, "direct fingerprint" of human activity on Earth, scientists...
Researchers at Massachusetts Institute of Technology say they have carried out a theoretical...
New findings by a Johns Hopkins Univ.-led team reveal long unknown details about carbon deep...
Univ. of Utah engineers have developed a polarizing filter that allows in more light, leading the way for mobile device displays that last much longer on a single battery charge and cameras that can shoot in dim light. Polarizers are indispensable in digital photography and LCD displays, but they block enormous amounts of light, wasting energy and making it more difficult to photograph in low light.
As hands come in left and right versions that are mirror images of each other, so do the amino acids and sugars within us. But unlike hands, only the left-oriented amino acids and the right-oriented sugars ever make into life as we know it. Scientists know the other varieties exist because when they synthesize these amino acids and sugars in a laboratory, roughly equal numbers of left- and right-facing arrangements form.
Univ. of California, Los Angeles biochemists have created the largest-ever protein that self-assembles into a molecular “cage.” The research could lead to synthetic vaccines that protect people from the flu, HIV and other diseases. At a size hundreds of times smaller than a human cell, it also could lead to new methods of delivering pharmaceuticals inside of cells, or to the creation of new nanoscale materials.
Univ. of Tennessee, Knoxville’s College of Engineering has made recent headlines for discoveries that, while atomically small, could impact our modern world. The team focused on the role of epilayer-substrate interactions in determining orientational relations in van der Waals epitaxy.
Researchers at the Univ. of Michigan have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders. Jiandie Lin of the Life Sciences Institute described how in mice the hormone, NRG4, is secreted by so-called brown fat cells and communicates with the liver to regulate the conversion of sugar into fat.
If LCD TVs get more colorful in the next few years, it will probably be thanks to QD Vision, a pioneer of quantum-dot television displays. Quantum dots are light-emitting semiconductor nanocrystals that can be tuned to emit all colors across the visible spectrum. By tuning these dots to red and green, and using a blue backlight to energize them, QD Vision has developed an optical component that can boost the color gamut for LCD televisions.
As the installation of photovoltaic solar cells continues to accelerate, scientists are looking for inexpensive materials beyond the traditional silicon that can efficiently convert sunlight into electricity. Theoretically, iron pyrite could do the job, but when it works at all, the conversion efficiency remains frustratingly low. Now, a Univ. of Wisconsin-Madison research team explains why that is.
Scientists at The Scripps Research Institute have identified weak spots on the surface of Ebola virus that are targeted by the antibodies in ZMapp, the experimental drug cocktail administered to several patients during the recent Ebola outbreak. The study provides a revealing 3-D picture of how the ZMapp antibodies bind to Ebola virus.
Massachusetts Institute of Technology chemists have developed new nanoparticles that can simultaneously perform magnetic resonance imaging (MRI) and fluorescent imaging in living animals. Such particles could help scientists to track specific molecules produced in the body, monitor a tumor’s environment, or determine whether drugs have successfully reached their targets.
Small pieces of synthetic RNA trigger a RNA interference (RNAi) response that holds great therapeutic potential to treat a number of diseases, especially cancer and pandemic viruses. The problem is delivery: It’s extremely difficult to get RNAi drugs inside the cells in which they are needed.
The race to make computer components smaller and faster and use less power is pushing the limits of the properties of electrons in a material. Photonic systems could eventually replace electronic ones, but the fundamentals of computation, mixing two inputs into a single output, currently require too much space and power when done with light.
Researchers at the Univ. of California, Los Angeles Henry Samueli School of Engineering and Applied Science have developed a more efficient way to turn methanol into useful chemicals, such as liquid fuels, and that would also reduce carbon dioxide emissions. Methanol, which is a product of natural gas, is well-known as a common “feedstock” chemical.
From a mechanical perspective, granular materials are stuck between a rock and a fluid place, with behavior resembling neither a solid nor a liquid. Think of sand through an hourglass: As grains funnel through, they appear to flow like water, but once deposited, they form a relatively stable mound, much like a solid.
Plants all over the world are more sensitive to drought than many experts realized, according to a new study by scientists at the Univ. of California, Los Angeles and China’s Xishuangbanna Tropical Botanical Garden. The research will improve predictions of which plant species will survive the increasingly intense droughts associated with global climate change.
While astronomers have observed the protoplanetary disk evolution throughout our galaxy, the mechanism by which planetary disks evolve at such a rapid rate has eluded scientists for decades. Now researchers have provided the first experimental evidence that our solar system’s protoplanetary disk was shaped by an intense magnetic field that drove a massive amount of gas into the sun within just a few million years.
Researches have uncovered "smoking-gun" evidence to confirm the workings of an emerging class of materials that could make possible "spintronic" devices and practical quantum computers far more powerful than today's technologies. The materials are called topological insulators.
Today’s climate models predict a 50% increase in lightning strikes across the U.S. during this century as a result of warming temperatures associated with climate change. Reporting in Science, a team of climate scientists look at predictions of precipitation and cloud buoyancy in 11 different climate models and conclude that their combined effect will generate more frequent electrical discharges to the ground.
Needles almost too small to be seen with the unaided eye could be the basis for new treatment options for two of the world’s leading eye diseases: glaucoma and corneal neovascularization. The microneedles, ranging in length from 400 to 700 microns, could provide a new way to deliver drugs to specific areas within the eye relevant to these diseases.
Massachusetts Institute of Technology (MIT) engineers have transformed the genome of the bacterium E. coli into a long-term storage device for memory. They envision that this stable, erasable and easy-to-retrieve memory will be well suited for applications such as sensors for environmental and medical monitoring.
After graphene was first produced in the laboratory in 2004, thousands of laboratories began developing graphene products worldwide. Researchers were amazed by its lightweight and ultra-strong properties. Ten years later, scientists now search for other materials that have the same level of potential.
It’s not uncommon to see cameras mounted on store ceilings, propped up in public places or placed inside subways, buses and even on the dashboards of cars. Cameras record our world down to the second. This can be a powerful surveillance tool on the roads and in buildings, but it’s surprisingly hard to sift through vast amounts of visual data to find pertinent information, until now.
Peering deep into time with one of the world’s newest, most sophisticated telescopes, astronomers have found a galaxy—AzTEC-3—that gives birth annually to 500 times the number of suns as the Milky Way galaxy, according to a new Cornell Univ.-led study published in the Astrophysical Journal.
When munched by grazing animals (or mauled by scientists in the laboratory), some herbaceous plants overcompensate, producing more plant matter and becoming more fertile than they otherwise would. Scientists say they now know how these plants accomplish this feat of regeneration. They report their findings in Molecular Ecology.
The rapidly melting ice sheets on the coast of West Antarctica are a potential major contributor to rising ocean levels worldwide. Although warm water near the coast is thought to be the main factor causing the ice to melt, the process by which this water ends up near the cold continent is not well understood. Using robotic ocean gliders, Caltech researchers now have a better understanding of the cause.
Researchers have demonstrated a new process to convert all biomass into liquid fuel, and the method could make possible mobile processing plants. The researchers at Purdue Univ. filed a patent application on the concept in 2008 and have now demonstrated that it works in laboratory experiments.
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