Chemists at The Scripps Research Institute have discovered a broad and strikingly inexpensive method for synthesizing “amines,” a class of organic compounds prominent in drugs and other modern products. The new reaction is particularly useful for synthesizing complex amines that would be highly valuable in pharmaceuticals, but are impractical—or impossible—to make with standard methods.
Where do electronics go when they die? Most devices are laid to eternal rest in landfills. But...
Last summer, MIT researchers published a paper describing an algorithm that can recover...
Type Ia supernovae, one of the most dazzling phenomena in the universe, are produced when small...
The latest version of a microfluidic device for capturing rare circulating tumor cells is the first designed specifically to capture clusters of two or more cells, rather than single cells. The new device, called the Cluster-Chip, was developed by the same Massachusetts General Hospital (MGH) research team that created previous microchip-based devices.
Graphene is a material with a host of potential applications, including in flexible light sources, solar panels that could be integrated into windows and membranes to desalinate and purify water. But all these possible uses face the same big hurdle: the need for a scalable and cost-effective method for continuous manufacturing of graphene films.
Ever since single-layer graphene burst onto the science scene in 2004, the possibilities for the promising material have seemed nearly endless. With its high electrical conductivity, ability to store energy, and ultra-strong and lightweight structure, graphene has potential for many applications in electronics, energy, the environment and even medicine.
A class of FDA-approved cancer drugs may be able to prevent problems with brain cell development associated with disorders including Down syndrome and Fragile X syndrome, researchers at the Univ. of Michigan Life Sciences Institute have found. The researchers' proof-of-concept study using fruit fly models of brain dysfunction was published in eLife.
Researchers have found a way to couple the properties of different 2-D materials to provide an exceptional degree of control over light waves. They say this has the potential to lead to new kinds of light detection, thermal management systems and high-resolution imaging devices.
Quantum computers are in theory capable of simulating the interactions of molecules at a level of detail far beyond the capabilities of even the largest supercomputers today. Such simulations could revolutionize chemistry, biology and materials science, but the development of quantum computers has been limited by the ability to increase the number of quantum bits, or qubits, that encode, store and access large amounts of data.
Biomedical devices that can be implanted in the body for drug delivery, tissue engineering or sensing can help improve treatment for many diseases. However, such devices are often susceptible to attack by the immune system, which can render them useless. A team of Massachusetts Institute of Technology researchers has come up with a way to reduce that immune-system rejection.
Fans of homebrewed beer and backyard distilleries already know how to employ yeast to convert sugar into alcohol. But a research team led by UC Berkeley bioengineers has gone much further by completing key steps needed to turn sugar-fed yeast into a microbial factory for producing morphine and potentially other drugs, including antibiotics and anti-cancer therapeutics.
Engineers have taken a step forward in creating the next generation of computers and mobile devices capable of speeds millions of times faster than current machines. The Utah engineers have developed an ultracompact beamsplitter for dividing light waves into two separate channels of information. The device brings researchers closer to producing silicon photonic chips that compute and shuttle data with light instead of electrons.
Stanford Univ. scientists have solved a long-standing mystery about methanogens, unique microorganisms that transform electricity and carbon dioxide into methane. In a new study, the Stanford team demonstrates for the first time how methanogens obtain electrons from solid surfaces. The discovery could help scientists design electrodes for microbial "factories" that produce methane gas and other compounds sustainably.
The compound eyes found in insects and some sea creatures are marvels of evolution. There, thousands of lenses work together to provide sophisticated information without the need for a sophisticated brain. Human artifice can only begin to approximate these naturally self-assembled structures, and, even then, they require painstaking manufacturing techniques.
Nanoengineers at the Univ. of California, San Diego developed a gel filled with toxin-absorbing nanosponges that could lead to an effective treatment for skin and wound infections caused by MRSA, an antibiotic-resistant bacteria. This "nanosponge-hydrogel" minimized the growth of skin lesions on mice infected with MRSA, without the use of antibiotics.
Scientists at MIT have developed a systematic approach to research its structure, blending computational modeling and mechanical analysis to 3D-print synthetic spider webs. These models offer insight into how spiders optimize their own webs.
Researchers have discovered the structure of a key protein on the surface of an unusually large virus called the mimivirus, aiding efforts to determine its hosts and unknown functions. The mimivirus was initially thought to be a bacterium because it is much larger than most viruses. It was isolated by French scientists in 1992 but wasn't confirmed to be a virus until 2003.
A new target for drug development in the fight against the deadly disease malaria has been discovered by researchers at Massachusetts Institute of Technology. In a recently published paper, the researchers describe how they identified the drug target while studying the way in which the parasites Toxoplasma gondii, which causes toxoplasmosis, and Plasmodium, which causes malaria, access vital nutrients from their host cells.
Fermions are the building blocks of matter, interacting in a multitude of permutations to give rise to the elements of the periodic table. Without fermions, the physical world would not exist. Examples of fermions are electrons, protons, neutrons, quarks and atoms consisting of an odd number of these elementary particles. Because of their fermionic nature, electrons and nuclear matter are difficult to understand theoretically.
Inspired by the way iridescent bird feathers play with light, scientists have created thin films of material in a wide range of pure colors with hues determined by physical structure rather than pigments. Structural color arises from the interaction of light with materials that have patterns on a minute scale, which bend and reflect light to amplify some wavelengths and dampen others.
Using a smart tablet and a red beam of light, Georgia Institute of Technology researchers have created a system that allows people to control a fleet of robots with the swipe of a finger. A person taps the tablet to control where the beam of light appears on a floor. The swarm robots then roll toward the illumination, constantly communicating with each other and deciding how to evenly cover the lit area.
A molecular switch that seems to be essential for embryonic heart cells to grow into more mature, adult-like heart cells has been discovered. The discovery should help scientist better understand how human hearts mature. Of particular interest to stem cell and regenerative medicine researchers, the finding may lead to laboratory methods to create heart cells that function more like those found in adult hearts.
By combining 3-D holographic lithography and 2-D photolithography, researchers from the Univ. of Illinois at Urbana-Champaign have demonstrated a high-performance 3-D microbattery suitable for large-scale on-chip integration with microelectronic devices.
Treatments used by traditional healers in Nigeria have inspired scientists at Northwestern Univ. to synthesize four new chemical compounds that could one day lead to better therapies for people with psychiatric disorders. In a recently published paper, the scientists detail how they created these natural compounds by completing the first total syntheses of two indole alkaloids: alstonine and serpentine.
A new technique invented at Massachusetts Institute of Technology can measure the relative positions of tiny particles as they flow through a fluidic channel, potentially offering an easy way to monitor the assembly of nanoparticles, or to study how mass is distributed within a cell. With further advancements, this technology has the potential to resolve the shape of objects in flow as small as viruses, the researchers say.
Climate helps drive the erosion process that exposes economically valuable copper deposits and shapes the pattern of their global distribution, according to a new study. Nearly three-quarters of the world's copper production comes from large deposits that form about 2 km beneath the Earth's surface, known as porphyry copper deposits.
Therapies that specifically target mutations in a person’s cancer have been much-heralded in recent years, yet cancer cells often find a way around them. To address this, researchers identified a promising combinatorial approach to treating glioblastomas, the most common form of primary brain cancer.
It’s hard to take a photo through a window without picking up reflections of the objects behind you. To solve that problem, professional photographers sometimes wrap their camera lenses in dark cloths affixed to windows by tape or suction cups. But that’s not a terribly attractive option for a traveler using a point-and-shoot camera to capture the view from a hotel room or a seat in a train.
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