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U.S. leads drug-approval race

The U.S. Food and Drug Administration (FDA) generally approves drug therapies faster and earlier than its counterparts in Canada and Europe, according to a new study by Yale University School of Medicine researchers. The study counters perceptions that the drug approval process in the U.S. is especially slow.

‘Smart’ microcapsules fabricated in a single step

‘Smart’ microcapsules fabricated in a single step

A new, single-step method of fabricating microcapsules using copolymers, gold nanoparticles, and small barrel-shaped molecules called cucurbiturils has been developed by researchers at the University of Cambridge, U.K. The capsules have potential applications medicine, agriculture, and diagnostics.

Breakthrough opens elusive compounds to drug research

Breakthrough opens elusive compounds to drug research

The family of complex compounds known as taxanes are exceedingly difficult to produce in the lab, limiting the use of Taxol, an important cancer drug, and hindering the discovery of related taxadienes. Scripps Research Institute scientists have found a way to simplify this process, potentially opening up new drug leads.

Chemists invent polarimeter with no moving parts

Certain compounds are so similar they are distinguished by the way interact with polarized light. A conventional polarimeter accomplishes this test by rotating a polarizing prism. A new device invented by two professors at Baylor Univ. eliminates this mechanical motion, and should improve measurement reliability in industries like pharmaceuticals.

Scientists develop compound that effectively halts progression of multiple sclerosis

Researchers at the Florida campus of The Scripps Research Institute have developed the first of a new class of highly selective compounds that effectively suppresses the severity of multiple sclerosis in animal models. The discovery also holds promise for other autoimmune disorders.

Turbo pumps meet the needs of pharma and food development

Turbo pumps meet the needs of pharma and food development

Edwards Vacuum has won a contract to supply Quorum Technologies with its EXT75DX turbomolecular vacuum pumps for cryogenic preparation chambers used in scanning electron microscopy applications. The oil-free pump allows Quorum to perform cold fracturing, controlled sublimation, and specimen coating for reliable microstructure analysis.

Report: Corporate R&D spending declined during 2009 downturn

Booz & Company this week released its Global Innovation 1000 Study, which details the first global corporate R&D spending drop since before 1997, the first year studied. However, R&D intensity increased as corporate revenues declined by nearly three times the rate of reductions in R&D spending.

Worldwide R&D expenditures top $330 billion

About 40,000 companies received questionnaires from the National Science Foundation and the U.S. Census Bureau in 2008. The results from this report, the first of its kind to gauge R&D performance on a global scale, show that the U.S. economy supports a higher level of domestic R&D ($234 billion) than some had thought.

Laser processes promise better artificial joints

Laser processes promise better artificial joints

Researchers are developing technologies that use lasers to create arterial stents and longer-lasting medical implants that could be manufactured 10 times faster and also less expensively than is now possible. One of the researchers' techniques works by depositing layers of a powdered mixture of metal and ceramic materials, melting the powder with a laser and then immediately solidifying each layer to form parts.

Novel polymer could improve protein-based drugs

A new method for attaching a large protective polymer molecule to a protein appears to improve protein drugs significantly. Bioengineers at Duke Univ. developed the new approach and demonstrated in an animal model that the newly created protein-polymer combinations, known as conjugates, remained in circulation significantly longer than an unprotected protein.

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R&D 100: Now and Then

R&D 100: Now and Then

As R&D Magazine prepares for the 50th annual R&D 100 Awards, the editors take a stroll through the awards history, and invite former winners to join them.

R&D 100 Awards: Final Deadline is April 30

R&D 100 Awards: Final Deadline is April 30

The editors of R&D Magazine have extended the submission deadline for the 2012 R&D 100 Awards to April 30, 2012, at 11:59 pm, eastern U.S. time. This is the FINAL DEADLINE. We cannot accept entries after that time.

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CC Radio - Episode 99

NIH bikes to work. For transcripts of this and other NIH Clinical Center podcasts, visit http://www.cc.nih.gov/podcast/

Blueshift - May 21, 2012: Astrophysicist to the Stars, Dr. David Saltzberg

In a follow-up to our previous interviews with co-creator of "The Big Bang Theory," Bill Prady, we interviewed Dr. David Saltzberg, the show's resident astrophysicist and science consultant. Find out more about his research, adventures in astrophysics, and how he keeps the science of the...

New To Market

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JEOL to launch world's smallest solid-state NMR probe
JEOL to launch world's smallest solid-state NMR probe

According to JEOL Resonance, a new benchmark for resolution and benchmark will be set with its introduction next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. The probe is capable of high resolution sample analysis by spinning the sample at 110 kHz, the world's fastest spinning speed for NMR.

Energy Harvesting Subsystems for Wireless Sensors

Nextreme Thermal Solutions has developed two new energy harvesting subsystems for the plumbing and HVAC industries. The subsystems are the latest additions to Nextreme's Thermobility energy harvesting platform that uses thin-film thermoelectric technology to convert available thermal energy into electric power for a variety of autonomous self-powered applications.

Tools & Technology

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Microscope System with LED Illumination
Microscope System with LED Illumination

Leica Microsystems has introduced the Leica DM4000 B LED, a microscope system with LED illumination suited for biomedical applications.

Liquid Handler

Gilson Inc. has introduced the GX-241 liquid handler, a compact liquid handler suited for application and laboratories where bench space is at a premium.

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