Vaccines
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Feb 8 | News
In an effort to better understand how a virus works to design better antiviral treatments, scientists have now quantified part of the physics of the virus. Specifically, they have measured the pent-up energy released when a virus enters a host cell and expels its viral DNA, turning the cell into a virus factory.
9/24/2009 | News
For the first time, an experimental vaccine formed from two
unsuccessful varieties has prevented infection with the AIDS virus, a watershed
event in the deadly epidemic and a surprising result. Recent failures led many
scientists to think such a vaccine might never be possible. Anthony Fauci,
director of the National Institute of Allergy and Infectious Disease, which
performed the study with the U.S. Army, was pleased by findings, but warned
that this is “not the end of the road".
9/15/2009 | News
Adjuvants, which are substances that increase immune
response when used in combination with a vaccine, are currently limited to just
one approved example for human use: aluminum hydroxide, or alum. But it’s a
weak example, and researchers at Oregon State Univ. now say they’ve developed a
much more powerful adjuvant based on nanoparticles prepared with lecithin.
9/14/2009 | News
The first such antibodies to found in more than a decade,
PG9 and PG16 were isolated from donors in developing countries by Scripps
Research Institute scientists. Unlike previously identified promising
antibodies which function by binding in places that have been difficult to exploit
by vaccine, these new targets attach to more promising sites on the HIV virus.
9/3/2009 | News
Stable antibodies could be used in stockpiled diagnostic and
detection kits that can survive in tough environments for years at a time. The
could also be used in durable pathogen-finding bionsensors, which is why
researchers at Argonne National Lab have been looking for ways to accomplish
stability without loss of function. They report that they are close to this
goal.
8/19/2009 | News
Good news for people fearful of needles and squeamish of shots: scientists report the design of a painless patch that may someday render hypodermic needles—as well as annual flu shots—a thing of the past. Lined with tiny “microneedles,” these patches could make treatment of diabetes and a wide range of other diseases safer, more effective and less painful. Used as tiny hypodermic needles, they could improve treatment of macular degeneration and other diseases of the eye.