Stem Cell Research

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Stem cell-growing surface enables bone repair

Stem cell-growing surface enables bone repair

University of Michigan researchers have proven that a special surface, free of biological contaminants, allows adult-derived stem cells to thrive and transform into multiple cell types. Their success brings stem cell therapies another step closer.

Physical properties predict stem cell outcome

Physical properties predict stem cell outcome

Tissue engineers can use mesenchymal stem cells derived from fat to make cartilage, bone, or more fat. The best cells to use are ones that are already likely to become the desired tissue. Brown University researchers have discovered that the mechanical properties of the stem cells can foretell what they will become, leading to a potential method of concentrating them for use in healing.

Team discovers new way to stimulate immune cells

A research team at Rutgers University has been able to take a new pharmacological approach to activate the immune cells to prevent cancer growth through stimulation of the opiate receptors found on immune cells.

Successful stem cell differentiation requires DNA compaction

Successful stem cell differentiation requires DNA compaction

New research findings show that embryonic stem cells unable to fully compact the DNA inside them cannot complete their primary task: differentiation into specific cell types that give rise to the various types of tissues and structures in the body. Researchers from the Georgia Institute of Technology and Emory University found that chromatin compaction is required for proper embryonic stem cell differentiation to occur.

Gene activation follows a circuitous route

Gene activation follows a circuitous route

In order to reactivate silenced genes, a cell needs to remove certain “off” markers called methyl groups from the DNA. Scientists have recently shown that this process involves an intermediate step and an enzyme that also plays a role in the development of blood cancer. The finding could lead to new ideas for cancer-fighting therapies.

Adult stem cells regenerate hair in mice

Adult stem cells regenerate hair in mice

A research group headed by the Tokyo University of Science has demonstrated the possibility of  regenerating functional hair adult stem cells. The bioengineered hair follicles grown in mice show full functionality, including surrounding host tissue connections and nerve fibers. The finding could represent a substantial advance in the development of next-generation of organ replacement regenerative therapies.

Texas OKs experimental stem cell therapy rules

The Texas Medical Board on Friday approved new rules on experimental stem cell therapies such as the one Gov. Rick Perry underwent during back surgery last year, despite objections they don't do enough to protect patients and could led to an explosion of doctors promoting unproven, expensive treatments.

How embryonic stem cells orchestrate human development

Yale University researchers show in detail how three genes within human embryonic stem cells regulate development, a finding that increases understanding of how to grow these cells for therapeutic purposes. This process is different in humans than in mice, highlighting the importance of research using human embryonic stem cells.

Somatic stem cells obtained from skin cells for the first time

Somatic stem cells obtained from skin cells for the first time

Scientists in Germany have succeeded in obtaining somatic stem cells from fully differentiated somatic cells without them first passing through the pluripotent stage. To perform this conversion, researchers combined a number of different growth factors, which are proteins that guide cellular growth.

Stem cells hint at potential treatment for Huntington's disease

Stem cells hint at potential treatment for Huntington's disease

Huntington's disease, the debilitating congenital neurological disorder that progressively robs patients of muscle coordination and cognitive ability, is a condition without effective treatment, a slow death sentence. But if researchers can build on new research, a special type of brain cell forged from stem cells could help restore the muscle coordination deficits that cause the uncontrollable spasms characteristic of the disease.

Blogs

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R&D 100: Now and Then

R&D 100: Now and Then

As R&D Magazine prepares for the 50th annual R&D 100 Awards, the editors take a stroll through the awards history, and invite former winners to join them.

R&D 100 Awards: Final Deadline is April 30

R&D 100 Awards: Final Deadline is April 30

The editors of R&D Magazine have extended the submission deadline for the 2012 R&D 100 Awards to April 30, 2012, at 11:59 pm, eastern U.S. time. This is the FINAL DEADLINE. We cannot accept entries after that time.

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CC Radio - Episode 99

NIH bikes to work. For transcripts of this and other NIH Clinical Center podcasts, visit http://www.cc.nih.gov/podcast/

Blueshift - May 21, 2012: Astrophysicist to the Stars, Dr. David Saltzberg

In a follow-up to our previous interviews with co-creator of "The Big Bang Theory," Bill Prady, we interviewed Dr. David Saltzberg, the show's resident astrophysicist and science consultant. Find out more about his research, adventures in astrophysics, and how he keeps the science of the...

New To Market

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JEOL to launch world's smallest solid-state NMR probe
JEOL to launch world's smallest solid-state NMR probe

According to JEOL Resonance, a new benchmark for resolution and benchmark will be set with its introduction next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. The probe is capable of high resolution sample analysis by spinning the sample at 110 kHz, the world's fastest spinning speed for NMR.

Energy Harvesting Subsystems for Wireless Sensors

Nextreme Thermal Solutions has developed two new energy harvesting subsystems for the plumbing and HVAC industries. The subsystems are the latest additions to Nextreme's Thermobility energy harvesting platform that uses thin-film thermoelectric technology to convert available thermal energy into electric power for a variety of autonomous self-powered applications.

Tools & Technology

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Microscope System with LED Illumination
Microscope System with LED Illumination

Leica Microsystems has introduced the Leica DM4000 B LED, a microscope system with LED illumination suited for biomedical applications.

Liquid Handler

Gilson Inc. has introduced the GX-241 liquid handler, a compact liquid handler suited for application and laboratories where bench space is at a premium.

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