Stem Cell Research

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Stem cells restore sight in mouse model

An international research team led by Columbia Univ. Medical Center successfully used mouse embryonic stem cells to replace diseased retinal cells and restore sight in a mouse model of retinitis pigmentosa.

Nanoscopic material enables cartilage to do what it doesn’t do naturally

Nanoscopic material enables cartilage to do what it doesn’t do naturally

Northwestern Univ. researchers are the first to design a bioactive nanomaterial that promotes the growth of new cartilage in vivo and without the use of expensive growth factors. Minimally invasive, the therapy activates the bone marrow stem cells and produces natural cartilage. No conventional therapy can do this.

3-D scaffold provides biodegradable structure for stem cell growth

3-D scaffold provides biodegradable structure for stem cell growth

Materials scientists at the Univ. of Washington have built a three-dimensional scaffold out of a natural material that mimics the binding sites for stem cells, allowing the cells to reproduce on a clean, biodegradable structure. Results show that human embryonic stem cells grow and multiply readily on the structure.

Cornell scientists create usable blood vessels from human stem cells

 Researchers at Weill Cornell Medical College have turned human embryonic and pluripotent stem cells into plentiful, functional endothelial cells, which are critical to the formation of blood vessels. The technique, which could support cardiovascular treatments, is significant because it increases the quantity of available cells 40-fold over previous approaches.

Stem cells transformed into pork

Stem cells transformed into pork

Believe it or not, there is an organization called the In-vitro Meat Consortium that is actively trying to grow “petri pork”. Although right this lab meat has less protein than conventional pork, the effort is getter closer to its goal: offering a green alternative to raising livestock.

Surgeons battle bone loss with stem cell scaffolds

Surgeons battle bone loss with stem cell scaffolds

By delivering stem cells directly to the injury site, doctors are able to augment existing scaffold approaches for healing damaged bone and increase bone growth rates, at least in rats. The Georgia Tech method, which uses cells derived from adult bone marrow and fetal amniotic fluid, shows promise.

Efficient genetic modification of human embryonic stem cells developed

Biologists have developed an efficient way to genetically modify human embryonic stem cells. Their approach, which uses bacterial artificial chromosomes to swap in defective copies of genes, will make possible the rapid development of stem cell lines that can both serve as models for human genetic diseases and as testbeds on which to screen potential treatments.

Scripps team aims to determine ethnic origin of stem cell lines

The availability of genetically diverse cell lines for cell replacement therapy and drug development could have important medical consequences, a possibility that is driving researchers to draw on result of the HapMap Project to identify stem cell origins. Discordance in ethnic origin between organ donors and recipients could influence medical outcomes for tissue transplantation.

New stem cell from human skin found

Despite the remarkable regenerative capacity of mammalian skin, an adult dermal stem cell has not yet been identified. Medical researchers are exploring the possibility of deriving stem cells from the dermis or the second layer of skin, and Univ. of Tennessee scientists now report they have found a group of cells that can participate in wound healing.

Efficiency in creating non-embryonic stem cells boosted 200 times

In a finding that brightens the prospects of stem cell therapy without relying on human embryo, a Scripts Research Institute team reports that they have found three specific chemicals that encourage fibroblasts—cells typically used for forming connective tissues—to transform into a stem-cell-like state at a much more efficient level and in half the time as previous methods.

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Much ado about next to nothing

Much ado about next to nothing

The recent review of the past 10 years of the National Nanotechnology Initiative--as presented by the President's Council of Advisors on Science and Technology--suggested the rise of nanomanufacturing as the near future of nanotechnology. But the actual proposed funding reflects a cautious approach, even about nanotech in general.

Lunar tires, space MRSA, and resonating microfluidics

Lunar tires, space MRSA, and resonating microfluidics

I typically attend the annual Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy each year in pursuit of specific coverage. This year, I sought out candidates for coverage in a vacuum technology article, and pulled together some instruments for a spectroscopy guide. But as busy as that kept me, it wasn’t all mass spectrometers and vacuum pumps on the show floor.  

Multimedia

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NuGard Coating Ashburn Hill

NuGard Coating Ashburn Hill

NuGard First Response Protective Clothing are lightweight coveralls, jackets, and pants that provide protection from heat and flame while keeping the wearers body temperature constant.

Multi-Touch Music Maker

Multi-Touch Music Maker

Professor David Wessel shows his multi-touch interface that uses computer technologies that allow him to experiment with fine controls to "caress" the instrument.

New To Market

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P2i showcases liquid repellent nano-coating for hearing aids
P2i showcases liquid repellent nano-coating for hearing aids

At the AudiologyNOW! 2010 show in San Diego next month, UK-based coatings company P2i will display their relatively new Aridion liquid-repellant nano-coating. Designed for exposure to humidity or sweat, the polymer layer is applied by a pulsed ion gas process that lower’s the hearing aid’s surface energy, coaxing water away from delicate components.

Submersible FlowCAM catches particle images and data in-situ and real-time

Fluid Imaging Technologies recently introduced its Submersible FlowCAM particle and cell imaging and analysis system at Ocean Sciences 2010 in Portland, Ore. The remote sensing platform can be used for continuous, unattended monitoring tethered to research vessels or autonomous submersibles.

Tools & Technology

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Benchtop NMR analyzer
Benchtop NMR analyzer

Oxford Instruments America, Inc.’s Magnetic Resonance Group released the second generation of its MQC analyzers.

Software solution for microarray image analysis

BioDiscovery Inc. released ImaGene 9.0 for microarray image analysis. The new features include improved memory performance for the latest high density arrays, streamlined processing pipeline focused on image quantification and intensity extraction, and new modular design with options to add modules for analysis of gene/miRNA expression or CGH data.

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