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Stem cell-growing surface enables bone repair

Stem cell-growing surface enables bone repair

University of Michigan researchers have proven that a special surface, free of biological contaminants, allows adult-derived stem cells to thrive and transform into multiple cell types. Their success brings stem cell therapies another step closer.

Discarded data may hold the key to a sharper view of molecules

There's nothing like a new pair of eyeglasses to bring fine details into sharp relief. For scientists who study the large molecules of life from proteins to DNA, the equivalent of new lenses have come in the form of an advanced method for analyzing data from X-ray crystallography experiments. The findings could lead to new understanding of the molecules that drive processes in biology, medical diagnostics, nanotechnology, and other fields.

Modified nanoparticle opens window on future gene editing technologies

The scientific and technological literature is abuzz with nanotechnology and its manufacturing and medical applications. But it is in an area with a less glitzy aura—plant sciences—where nanotechnology advancements are contributing dramatically to agriculture. Researchers at Iowa State University have now demonstrated the ability to deliver proteins and DNA into plant cells, simultaneously.

Project to examine 'Yeti' DNA

A new collaboration between Oxford University and the Lausanne Museum of Zoology will use the latest genetic techniques to investigate organic remains that some have claimed belong to the 'Yeti' and other 'lost' hominid species.

Deconstructing the cell's most complex structure

One of the most important structures in a cell is the nuclear pore complex—a tiny yet complicated channel through which information flows in and out of the cell's nucleus, directing all other cell activity. Little is known about this vital cell structure, but a Massachusetts Institute of Technology biologist is trying to change that.

Researchers develop way to strengthen proteins with polymers

Researchers develop way to strengthen proteins with polymers

In a new study, investigators from the University of California, Los Angeles describe how they synthesized polymers to attach to proteins in order to stabilize them during shipping, storage, and other activities. The study findings suggest that these polymers could be useful in stabilizing protein formulations.

Mapping the crocodile genome is not for the faint of heart

Mapping the crocodile genome is not for the faint of heart

Catching a crocodile or alligator to obtain a blood sample for testing is often done at night by a boat or a canoe. A snout snare eases the process, but it’s still a nerve-wracking experience. The samples are for the first mapping project for crocodile and alligator genomes, and it’s also the among the first such efforts to be done on a reptile species.

Physical properties predict stem cell outcome

Physical properties predict stem cell outcome

Tissue engineers can use mesenchymal stem cells derived from fat to make cartilage, bone, or more fat. The best cells to use are ones that are already likely to become the desired tissue. Brown University researchers have discovered that the mechanical properties of the stem cells can foretell what they will become, leading to a potential method of concentrating them for use in healing.

Building a model to explain how cells grow

Building a model to explain how cells grow

A collaboration between Lehigh University physicists and University of Miami biologists addresses an important fundamental question in basic cell biology: How do living cells figure out when and where to grow?

Neurotransmission is controlled by a single protein

Scientists at Weill Cornell Medical College have discovered that the single protein, alpha 2 delta, exerts a spigot-like function that controls the volume of neurotransmitters and other chemicals that flow between the synapses of brain neurons. The surprising finding tells us not only how brain cells communicate, but also how a certain pain drug works.

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R&D 100: Now and Then

R&D 100: Now and Then

As R&D Magazine prepares for the 50th annual R&D 100 Awards, the editors take a stroll through the awards history, and invite former winners to join them.

R&D 100 Awards: Final Deadline is April 30

R&D 100 Awards: Final Deadline is April 30

The editors of R&D Magazine have extended the submission deadline for the 2012 R&D 100 Awards to April 30, 2012, at 11:59 pm, eastern U.S. time. This is the FINAL DEADLINE. We cannot accept entries after that time.

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CC Radio - Episode 99

NIH bikes to work. For transcripts of this and other NIH Clinical Center podcasts, visit http://www.cc.nih.gov/podcast/

Blueshift - May 21, 2012: Astrophysicist to the Stars, Dr. David Saltzberg

In a follow-up to our previous interviews with co-creator of "The Big Bang Theory," Bill Prady, we interviewed Dr. David Saltzberg, the show's resident astrophysicist and science consultant. Find out more about his research, adventures in astrophysics, and how he keeps the science of the...

New To Market

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JEOL to launch world's smallest solid-state NMR probe
JEOL to launch world's smallest solid-state NMR probe

According to JEOL Resonance, a new benchmark for resolution and benchmark will be set with its introduction next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. The probe is capable of high resolution sample analysis by spinning the sample at 110 kHz, the world's fastest spinning speed for NMR.

Energy Harvesting Subsystems for Wireless Sensors

Nextreme Thermal Solutions has developed two new energy harvesting subsystems for the plumbing and HVAC industries. The subsystems are the latest additions to Nextreme's Thermobility energy harvesting platform that uses thin-film thermoelectric technology to convert available thermal energy into electric power for a variety of autonomous self-powered applications.

Tools & Technology

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Microscope System with LED Illumination
Microscope System with LED Illumination

Leica Microsystems has introduced the Leica DM4000 B LED, a microscope system with LED illumination suited for biomedical applications.

Liquid Handler

Gilson Inc. has introduced the GX-241 liquid handler, a compact liquid handler suited for application and laboratories where bench space is at a premium.

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