Genetic Engineering

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Our defensive chemical sensors are almost as ancient as vision

 The detection of tissue-damaging pungent chemicals like those found in wasabi, tear gas and cigarette smoke is called chemical nociception. It’s different than either taste or smell, and according to recent phylogenetics research, this defensive sensor has been conserved across 500 million years of evolution.

Personal look at genes locates disease causes

Personal look at genes locates disease causes

Children inherit about 30 mutated genes from each parent, fewer than had been thought, but enough in at least one case to pass on inherited illnesses, according to a first detailed look at the blueprint for human life in a family. Genomic analysis is proving useful for diagnosing the origins of sometimes mysterious diseases.

Universal DNA reader to advance faster, cheaper sequencing efforts

Universal DNA reader to advance faster, cheaper sequencing efforts

Arizona State scientists have come up with a new twist in their efforts to develop a faster and cheaper way to read the DNA genetic code. They have developed the first, versatile DNA reader that can discriminate between DNA's four core chemical components—the key to unlocking the vital code behind human heredity and health.

Synthetic gene-like crystals created for carbon dioxide capture

Synthetic gene-like crystals created for carbon dioxide capture

UCLA chemists report creating a synthetic "gene" that could capture heat-trapping carbon dioxide emissions, which contribute to global warming, rising sea levels, and the increased acidity of oceans.

Was Mendel Darwin’s Missed Opportunity?

Was Mendel Darwin’s Missed Opportunity?

The editors at Wired Magazine have pointed out that today is the anniversary of Gregor Mendel's presentation of a painstakingly produced paper about his breeding experiments on some 28,000 pea plants. It's too bad that Charles Darwin, who was sent a copy in 1866, never bothered to read it.

Carnegie Mellon first to measure energy released from virus during infection

In an effort to better understand how a virus works to design better antiviral treatments, scientists have now quantified part of the physics of the virus. Specifically, they have measured the pent-up energy released when a virus enters a host cell and expels its viral DNA, turning the cell into a virus factory.

HIV puzzle solved after 20 years of trying

Researchers in the UK and the U.S. have together grown a crystal that reveals the structure of an enzyme called integrase, which is found in retroviruses like HIV that use it to paste a copy of its genetic code into infected DNA. New antiretroviral drugs block integrase, but until now scientists didn’t know exactly how they worked.

Researchers develop new tool for gene delivery

Researchers at Tufts Univ. have developed a new tool for gene therapy that increases gene delivery to cells in the retina compared to other carriers and DNA alone. The tool provides a vehicle for therapeutic genes and may help researchers develop therapies for degenerative eye disorders such as retinitis pigmentosa and age-related macular degeneration.

Researchers engineer a new way to study hepatitis C

Researchers engineer a new way to study hepatitis C

Researchers at MIT and Rockefeller Univ. have successfully grown hepatitis C virus in otherwise healthy liver cells in the laboratory, an advance that could allow scientists to develop and test new treatments for the disease.

First rewire of genetic switches achieved

A team of scientists from the Univ. of Manchester have found a way of hijacking so-called ‘riboswitches’ and directing gene activity. Working within cells of bacteria, the team rewired these genetic switches so they are no longer activated by small naturally occurring molecules found in cells—but through the addition of a synthetic molecule.

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Much ado about next to nothing

Much ado about next to nothing

The recent review of the past 10 years of the National Nanotechnology Initiative--as presented by the President's Council of Advisors on Science and Technology--suggested the rise of nanomanufacturing as the near future of nanotechnology. But the actual proposed funding reflects a cautious approach, even about nanotech in general.

Lunar tires, space MRSA, and resonating microfluidics

Lunar tires, space MRSA, and resonating microfluidics

I typically attend the annual Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy each year in pursuit of specific coverage. This year, I sought out candidates for coverage in a vacuum technology article, and pulled together some instruments for a spectroscopy guide. But as busy as that kept me, it wasn’t all mass spectrometers and vacuum pumps on the show floor.  

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NuGard Coating Ashburn Hill

NuGard Coating Ashburn Hill

NuGard First Response Protective Clothing are lightweight coveralls, jackets, and pants that provide protection from heat and flame while keeping the wearers body temperature constant.

Multi-Touch Music Maker

Multi-Touch Music Maker

Professor David Wessel shows his multi-touch interface that uses computer technologies that allow him to experiment with fine controls to "caress" the instrument.

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P2i showcases liquid repellent nano-coating for hearing aids
P2i showcases liquid repellent nano-coating for hearing aids

At the AudiologyNOW! 2010 show in San Diego next month, UK-based coatings company P2i will display their relatively new Aridion liquid-repellant nano-coating. Designed for exposure to humidity or sweat, the polymer layer is applied by a pulsed ion gas process that lower’s the hearing aid’s surface energy, coaxing water away from delicate components.

Submersible FlowCAM catches particle images and data in-situ and real-time

Fluid Imaging Technologies recently introduced its Submersible FlowCAM particle and cell imaging and analysis system at Ocean Sciences 2010 in Portland, Ore. The remote sensing platform can be used for continuous, unattended monitoring tethered to research vessels or autonomous submersibles.

Tools & Technology

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Benchtop NMR analyzer
Benchtop NMR analyzer

Oxford Instruments America, Inc.’s Magnetic Resonance Group released the second generation of its MQC analyzers.

Software solution for microarray image analysis

BioDiscovery Inc. released ImaGene 9.0 for microarray image analysis. The new features include improved memory performance for the latest high density arrays, streamlined processing pipeline focused on image quantification and intensity extraction, and new modular design with options to add modules for analysis of gene/miRNA expression or CGH data.

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