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Stinky frogs are a treasure trove of antibiotic substances

Stinky frogs are a treasure trove of antibiotic substances

Recent research in China on amphibians so smelly that scientists term them “odorous frogs” has revealed a potentially rich source of new antibiotics. They concluded that these frogs possess the greatest diversity of germ-killing peptides.

Nature's medicine cabinet could yield hundreds of new drugs

According to a new analysis by a New York Botanical Garden scientist, there are probably at least 500 medically useful chemicals awaiting discovery in plant species whose chemical constituents have not yet been evaluated for their potential to cure or treat disease.

Gene therapy boosts blood-clotting for hemophiliacs

In what's being called a landmark study, researchers used gene therapy to successfully treat six patients with severe hemophilia, a blood-clotting disorder. The six men each received a single, 20-minute infusion of healthy genetic material delivered by a virus found in monkeys. Four of the patients were able to stop conventional blood-clotting treatments altogether.

Danish mushroom could be cancer fighter

Danish mushroom could be cancer fighter

In Denmark, mushrooms have primarily been used in food preparation or as intoxicants. But until. Dr. Ming Chen, an expert in traditional Chinese medicine, came along, nobody had discovered than a certain type of toxic mushroom was actually effective and selective against cancer cells.

An alternative to antibiotics?

An alternative to antibiotics?

Antibiotics are among the greatest achievements of medical science. But bacteria are increasingly developing resistance to once-potent drugs. Researchers are scrambling for an alternative, and researchers in Germany say they have found one in a therapeutic equivalent that could replace penicillin and related pharmaceuticals.

Growth-factor-containing nanoparticles accelerate healing of chronic wounds

Massachusetts General Hospital  investigators have developed a novel system for delivery of growth factors to chronic wounds such as pressure sores and diabetic foot ulcers. They fabricated nanospheres containing keratinocyte growth factor. When suspended in a fibrin gel, these nanoparticles improved the healing of deep skin wounds in diabetic mice.

Plasma therapy: An alternative to antibiotics?

Plasma therapy: An alternative to antibiotics?

A team of Russian and German researchers showed that a ten-minute treatment with low-temperature plasma was not only able to kill drug-resistant bacteria causing wound infections in rats but also increased the rate of wound healing.

Body clock drug could ease jet lag

Researchers in England report they have successfully reset and restarted the natural 24-hour body clock of mice in the lab using drugs alone. By manipulating a complex interaction of molecules and enzymes--in particular, slowing casein kinase 1 down--researchers controlled how quickly the circadian rhythm clock “ticks”.

Body’s own stem cells can lead to tooth regeneration

Body’s own stem cells can lead to tooth regeneration

A technique pioneered at Columbia University Medical Center can orchestrate stem cells to migrate to a 3-D scaffold infused with growth factor, holding the potential to yield an anatomically correct tooth in as soon as nine weeks once implanted. If successful, the in vivo method—the first of its kind—could lessen the need for dentures.

Magnetic fields could anchor therapy for vascular disease

Magnetic fields could anchor therapy for vascular disease

Scientists at the The Children’s Hospital of Philadelphia have demonstrated, in animals, the ability to drive iron-bearing nanoparticles to metal stents in injured blood vessels, where they deliver a drug payload that prevents blockages. The technique improved on conventional non-magnetic therapies, and at lower dosages.

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R&D 100: Now and Then

R&D 100: Now and Then

As R&D Magazine prepares for the 50th annual R&D 100 Awards, the editors take a stroll through the awards history, and invite former winners to join them.

R&D 100 Awards: Final Deadline is April 30

R&D 100 Awards: Final Deadline is April 30

The editors of R&D Magazine have extended the submission deadline for the 2012 R&D 100 Awards to April 30, 2012, at 11:59 pm, eastern U.S. time. This is the FINAL DEADLINE. We cannot accept entries after that time.

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CC Radio - Episode 99

NIH bikes to work. For transcripts of this and other NIH Clinical Center podcasts, visit http://www.cc.nih.gov/podcast/

Blueshift - May 21, 2012: Astrophysicist to the Stars, Dr. David Saltzberg

In a follow-up to our previous interviews with co-creator of "The Big Bang Theory," Bill Prady, we interviewed Dr. David Saltzberg, the show's resident astrophysicist and science consultant. Find out more about his research, adventures in astrophysics, and how he keeps the science of the...

New To Market

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JEOL to launch world's smallest solid-state NMR probe
JEOL to launch world's smallest solid-state NMR probe

According to JEOL Resonance, a new benchmark for resolution and benchmark will be set with its introduction next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. The probe is capable of high resolution sample analysis by spinning the sample at 110 kHz, the world's fastest spinning speed for NMR.

Energy Harvesting Subsystems for Wireless Sensors

Nextreme Thermal Solutions has developed two new energy harvesting subsystems for the plumbing and HVAC industries. The subsystems are the latest additions to Nextreme's Thermobility energy harvesting platform that uses thin-film thermoelectric technology to convert available thermal energy into electric power for a variety of autonomous self-powered applications.

Tools & Technology

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Microscope System with LED Illumination
Microscope System with LED Illumination

Leica Microsystems has introduced the Leica DM4000 B LED, a microscope system with LED illumination suited for biomedical applications.

Liquid Handler

Gilson Inc. has introduced the GX-241 liquid handler, a compact liquid handler suited for application and laboratories where bench space is at a premium.

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