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Study: DNA vaccine and duck eggs protect against hantavirus disease

The highly pathogenic hantavirus causes a condition known as hantavirus pulmonary syndrome (HPS), which has a case fatality rate of 35-40%. To help the fight against a disease that has no vaccine, U.S. Army scientists and industry collaborators have successfully protected laboratory animals from lethal hantavirus disease using a novel approach that combines DNA vaccines and duck eggs.

Nanoparticle shape may be key for delivery to cancer cells

Scientists had originally thought they could create a “magic bullet” to patrol for cancer cells in the body, but only 5% of injected nanoparticles reach the targeted tumor using current delivery techniques. A Johns Hopkins University scientist is now working on techniques to specify nanoparticle size and shape and improve the chances that the drug will find its target.

Paralyzed woman uses her mind to control robot arm

Paralyzed woman uses her mind to control robot arm

Not long after a partially paralyzed man in Switzerland used his mind to remotely control a small robot, a Massachusetts woman paralyzed for 15 years used only her thoughts to direct a robotic arm to pick up a bottle of coffee and bring it to her lips But will the experimental brain-controlled technology ever help paralyzed people in everyday life?

Team discovers new way to stimulate immune cells

A research team at Rutgers University has been able to take a new pharmacological approach to activate the immune cells to prevent cancer growth through stimulation of the opiate receptors found on immune cells.

Is a new form of life really so alien?

A new essay in the journal PLoS Biology, examines what really constitutes “life” and the probability of discovering new life forms. Gerald Joyce, from The Scripps Research Institute, discusses in the essay the basic requirements for a life form to exist, and how it might fit into the forms alien life could take.

Gene activation follows a circuitous route

Gene activation follows a circuitous route

In order to reactivate silenced genes, a cell needs to remove certain “off” markers called methyl groups from the DNA. Scientists have recently shown that this process involves an intermediate step and an enzyme that also plays a role in the development of blood cancer. The finding could lead to new ideas for cancer-fighting therapies.

New software matches more kidney donations, faster

New software matches more kidney donations, faster

Using game theory and market dynamices, Harvard University economist Alvin Roth has helped develop a suite of computer programs that match living kidney donors with recipients. The software comprehensively addresses the common limitations of this complicated process, matching participants with compatible blood types and antibodies.

New form of spectroscopy tracks differentiating cells in real time

New form of spectroscopy tracks differentiating cells in real time

With the development of synchrotron infrared spectroscopy, scientists at Lawrence Berkeley National Laboratory have observed, in real time the process of protein phosphorylation—a chemical interaction that controls everything from cell proliferation to differentiation to metabolism—in living cells stimulated by nerve growth factor.

Bioluminescent technology enables easy tracking of GMO

Careful handling and sampling techniques are required to assess the genetically modified content of a crop. The most common technique is polymerase chain reaction (PCR), but it involves complex extraction procedures and rapid thermocycling. Researchers have found that bioluminescent reporters, coupled with isolated amplification, provide sufficient accuracy with far less hassle.

Specific enzyme could slow aging in astronauts, elderly

New research suggests that the 5-lipoxygenase enzyme plays an important role in the microgravity-induced cell death that affects astronauts’ immune systems. Forced inhibition of this enzyme’s activity could help astronauts and also lead to therapeutics for the elderly.

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R&D 100: Now and Then

R&D 100: Now and Then

As R&D Magazine prepares for the 50th annual R&D 100 Awards, the editors take a stroll through the awards history, and invite former winners to join them.

R&D 100 Awards: Final Deadline is April 30

R&D 100 Awards: Final Deadline is April 30

The editors of R&D Magazine have extended the submission deadline for the 2012 R&D 100 Awards to April 30, 2012, at 11:59 pm, eastern U.S. time. This is the FINAL DEADLINE. We cannot accept entries after that time.

Multimedia

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CC Radio - Episode 99

NIH bikes to work. For transcripts of this and other NIH Clinical Center podcasts, visit http://www.cc.nih.gov/podcast/

Blueshift - May 21, 2012: Astrophysicist to the Stars, Dr. David Saltzberg

In a follow-up to our previous interviews with co-creator of "The Big Bang Theory," Bill Prady, we interviewed Dr. David Saltzberg, the show's resident astrophysicist and science consultant. Find out more about his research, adventures in astrophysics, and how he keeps the science of the...

New To Market

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JEOL to launch world's smallest solid-state NMR probe
JEOL to launch world's smallest solid-state NMR probe

According to JEOL Resonance, a new benchmark for resolution and benchmark will be set with its introduction next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. The probe is capable of high resolution sample analysis by spinning the sample at 110 kHz, the world's fastest spinning speed for NMR.

Energy Harvesting Subsystems for Wireless Sensors

Nextreme Thermal Solutions has developed two new energy harvesting subsystems for the plumbing and HVAC industries. The subsystems are the latest additions to Nextreme's Thermobility energy harvesting platform that uses thin-film thermoelectric technology to convert available thermal energy into electric power for a variety of autonomous self-powered applications.

Tools & Technology

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Microscope System with LED Illumination
Microscope System with LED Illumination

Leica Microsystems has introduced the Leica DM4000 B LED, a microscope system with LED illumination suited for biomedical applications.

Liquid Handler

Gilson Inc. has introduced the GX-241 liquid handler, a compact liquid handler suited for application and laboratories where bench space is at a premium.

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