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Scientists decipher bacterial injection needles at atomic resolution

Scientists decipher bacterial injection needles at atomic resolution

Hundreds of tiny hollow needles stick out of the membrane of a bacteria that causes cholera. These are treacherous tools that makes bacterial pathogens so dangerous. Researchers in the U.S. and Germany have now seen this structure in 3D detail at atomic resolution. The images may help drug researchers.

Portable diagnostics designed to be shaken, not stirred

Portable diagnostics designed to be shaken, not stirred

As medical researchers and engineers try to shrink diagnostics to fit in a person's pocket, one question is how to easily move and mix small samples of liquid. University of Washington researchers have built and patented a surface that, when shaken, moves drops along certain paths to conduct medical or environmental tests.

New research brings satellite measurements, global climate models closer

One popular climate record that shows a slower atmospheric warming trend than other studies contains a data calibration problem, and when the problem is corrected the results fall in line with other records and climate models, according to a new University of Washington study.

Fossil raindrop impressions imply greenhouse gases loaded early atmosphere

Fossil raindrop impressions imply greenhouse gases loaded early atmosphere

Evidence from fossilized raindrop impressions dating 2.7 billion years ago, discovered by University of Washington researchers, indicates an abundance of greenhouse gases most likely caused the warm temperatures on ancient Earth.

Tiny reader makes fast, cheap DNA sequencing feasible

Tiny reader makes fast, cheap DNA sequencing feasible

Researchers have devised a nanoscale sensor to electronically read the sequence of a single DNA molecule, a technique that is fast and inexpensive and could make DNA sequencing widely available. The technique could lead to affordable personalized medicine, potentially revealing predispositions for afflictions such as cancer, diabetes, or addiction.

Ferroelectric switching discovered in soft biological tissue

Ferroelectric switching discovered in soft biological tissue

The heart's inner workings are mysterious, perhaps even more so with a new finding. Engineers at the University of Washington have discovered an electrical property in arteries not seen before in mammalian tissues. The researchers found that the wall of the aorta exhibits ferroelectricity, a response to an electric field known to exist in inorganic and synthetic materials.

'Open-source' robotic surgery platform going to medical research labs

'Open-source' robotic surgery platform going to medical research labs

Robotics experts at the University of California, Santa Cruz and the University of Washington have completed a set of seven advanced robotic surgery systems for use by major medical research laboratories throughout the United States.

What bacteria don’t know can hurt them

What bacteria don’t know can hurt them

Many infections, even those caused by antibiotic-sensitive bacteria, resist treatment. It’s paradox has vexed physicians for decades, and makes some infections impossible to cure. However, researchers have recently made the surprising discovery that interfering with the ability of biofilm-forming bacteria to sense starvation increases their susceptibility to antibiotics.

Paper uncovers power of Foldit gamers' strategies

Gamers made headlines in September for unraveling the structure of a protein central to research on AIDS. In a paper published this week, University of Washington researchers reveal the creative power of Foldit players' strategies and compare them to the best-known scientist-developed methods.

Proton-based transistor could let machines communicate with living things

Proton-based transistor could let machines communicate with living things

Human devices, from light bulbs to iPods, send information using electrons. Human bodies and all other living things, on the other hand, send signals and perform work using ions or protons. Materials scientists at the University of Washington have built a novel transistor that uses protons, creating a key piece for devices that can communicate directly with living things.

Blogs

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R&D 100: Now and Then

R&D 100: Now and Then

As R&D Magazine prepares for the 50th annual R&D 100 Awards, the editors take a stroll through the awards history, and invite former winners to join them.

R&D 100 Awards: Final Deadline is April 30

R&D 100 Awards: Final Deadline is April 30

The editors of R&D Magazine have extended the submission deadline for the 2012 R&D 100 Awards to April 30, 2012, at 11:59 pm, eastern U.S. time. This is the FINAL DEADLINE. We cannot accept entries after that time.

Multimedia

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CC Radio - Episode 99

NIH bikes to work. For transcripts of this and other NIH Clinical Center podcasts, visit http://www.cc.nih.gov/podcast/

Blueshift - May 21, 2012: Astrophysicist to the Stars, Dr. David Saltzberg

In a follow-up to our previous interviews with co-creator of "The Big Bang Theory," Bill Prady, we interviewed Dr. David Saltzberg, the show's resident astrophysicist and science consultant. Find out more about his research, adventures in astrophysics, and how he keeps the science of the...

New To Market

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JEOL to launch world's smallest solid-state NMR probe
JEOL to launch world's smallest solid-state NMR probe

According to JEOL Resonance, a new benchmark for resolution and benchmark will be set with its introduction next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. The probe is capable of high resolution sample analysis by spinning the sample at 110 kHz, the world's fastest spinning speed for NMR.

Energy Harvesting Subsystems for Wireless Sensors

Nextreme Thermal Solutions has developed two new energy harvesting subsystems for the plumbing and HVAC industries. The subsystems are the latest additions to Nextreme's Thermobility energy harvesting platform that uses thin-film thermoelectric technology to convert available thermal energy into electric power for a variety of autonomous self-powered applications.

Tools & Technology

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Microscope System with LED Illumination
Microscope System with LED Illumination

Leica Microsystems has introduced the Leica DM4000 B LED, a microscope system with LED illumination suited for biomedical applications.

Liquid Handler

Gilson Inc. has introduced the GX-241 liquid handler, a compact liquid handler suited for application and laboratories where bench space is at a premium.

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