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Nanoparticle shape may be key for delivery to cancer cells

Scientists had originally thought they could create a “magic bullet” to patrol for cancer cells in the body, but only 5% of injected nanoparticles reach the targeted tumor using current delivery techniques. A Johns Hopkins University scientist is now working on techniques to specify nanoparticle size and shape and improve the chances that the drug will find its target.

Phase-change breakthrough could transform memory media

Phase-change breakthrough could transform memory media

By using diamond-tipped tools to apply pressure, a team led by Johns Hopkins engineers has discovered some previously unknown electrical properties of a common memory material, a mix of germanium, antimony, and tellurium called GST. The discovery should make GST more useful for electronics developers by allowing memory formats that retain data more quickly, last longer, and allow far more capacity.

3D nano boxes self-assemble with precision

3D nano boxes self-assemble with precision

Without any tweezers or human intervention, nano boxes and other higher-order polyhedra have been self-assembled by engineers at Johns Hopkins University and mathematicians at Brown University. The process depends on flattening the panels of the structures and relying on the interaction of thermal changes and surface tension.

Baby crystal discovery may have solar power applications

Baby crystal discovery may have solar power applications

Using a combination of computer modeling and laboratory experiments, researchers at Johns Hopkins University and other institutions, have determined the smallest crystal configuration, or as they call it, a “baby crystal,” of lead sulfide. In this form, just 32 units large, the crystals show the same structural properties as they would at the macroscale.

Electric fish weak on charge, strong on adaptation

Electric fish weak on charge, strong on adaptation

An electric eel can generate enough current to stun its prey, just like a Taser. Weakly electric fish can also generate electricity, but not enough to do any harm. However, researchers have found that the animal’s ability to use an electric field to communicate, navigate, and hunt offers inspiration for a variety of engineering projects.

A close-up view of Mercury

A close-up view of Mercury

New observations from a spacecraft orbiting Mercury have revealed that the tiny, pockmarked planet harbors a highly unusual interior—and the craft's glimpse of Mercury's surface topography suggests the planet has had a very dynamic history.

Studying butterfly flight to help build bug-size flying robots

Studying butterfly flight to help build bug-size flying robots

To improve the next generation of insect-size flying machines, Johns Hopkins engineers have been aiming high-speed video cameras at some of the prettiest bugs on the planet. By figuring out how butterflies flutter among flowers with amazing grace and agility, the researchers hope to help small airborne robots mimic these maneuvers.

Researchers find best routes to self-assembling 3D shapes

Researchers find best routes to self-assembling 3D shapes

Researchers at Brown and Johns Hopkins universities have found optimal configurations for creating 3D geometric shapes. The Brown team developed the algorithmic tools, and the Johns Hopkins team tested  selected configurations. The research may lead to advances from drug-delivery containers to 3D sensors and electronic circuits.

Scientists chart gene expression in the brain across lifespan

Scientists chart gene expression in the brain across lifespan

A new study by Johns Hopkins Bloomberg School of Public Health and other institutes traced genetic changes in the brain during a lifetime, has found surprising reversals after fetal development and connected to Alzheimer’s disease findings. Previous investigations have combined transcriptional and genetic analyses in human cell lines, but few have applied these techniques to human neural tissue.

Paralyzed man uses mind-powered robot arm to touch

For the first time in the seven years since a motorcycle accident left him a quadriplegic, Tim Hennes recently was able to reach out to someone. Using only his thoughts, he was able to control robotic arm designed at Johns Hopkins University Applied Physics Laboratory. It wasn’t his real arm, but it was close.

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R&D 100: Now and Then

R&D 100: Now and Then

As R&D Magazine prepares for the 50th annual R&D 100 Awards, the editors take a stroll through the awards history, and invite former winners to join them.

R&D 100 Awards: Final Deadline is April 30

R&D 100 Awards: Final Deadline is April 30

The editors of R&D Magazine have extended the submission deadline for the 2012 R&D 100 Awards to April 30, 2012, at 11:59 pm, eastern U.S. time. This is the FINAL DEADLINE. We cannot accept entries after that time.

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CC Radio - Episode 99

NIH bikes to work. For transcripts of this and other NIH Clinical Center podcasts, visit http://www.cc.nih.gov/podcast/

Blueshift - May 21, 2012: Astrophysicist to the Stars, Dr. David Saltzberg

In a follow-up to our previous interviews with co-creator of "The Big Bang Theory," Bill Prady, we interviewed Dr. David Saltzberg, the show's resident astrophysicist and science consultant. Find out more about his research, adventures in astrophysics, and how he keeps the science of the...

New To Market

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JEOL to launch world's smallest solid-state NMR probe
JEOL to launch world's smallest solid-state NMR probe

According to JEOL Resonance, a new benchmark for resolution and benchmark will be set with its introduction next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. The probe is capable of high resolution sample analysis by spinning the sample at 110 kHz, the world's fastest spinning speed for NMR.

Energy Harvesting Subsystems for Wireless Sensors

Nextreme Thermal Solutions has developed two new energy harvesting subsystems for the plumbing and HVAC industries. The subsystems are the latest additions to Nextreme's Thermobility energy harvesting platform that uses thin-film thermoelectric technology to convert available thermal energy into electric power for a variety of autonomous self-powered applications.

Tools & Technology

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Microscope System with LED Illumination
Microscope System with LED Illumination

Leica Microsystems has introduced the Leica DM4000 B LED, a microscope system with LED illumination suited for biomedical applications.

Liquid Handler

Gilson Inc. has introduced the GX-241 liquid handler, a compact liquid handler suited for application and laboratories where bench space is at a premium.

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