Olympus has introduced a new multiphoton microscope system that allows researchers to achieve more sensitive, fast live cell imaging. The FluoView FV1200MPE multiphoton biological laser scanning imaging system is designed to deliver optimal live cell and tissue imaging. It offers increased laser selection, cooled high-sensitivity detector technology, increased scanhead light throughput, and new software features designed for high-speed functional measurements. The system can be built on the company's IX83 automated inverted microscope platform in addition to its BX61WI microscope for dipping-lens and live-animal applications. A confocal version of the microscope was also introduced.

The multiphoton system takes advantage of enhanced transmission benefits by supporting the Insight laser system from Newport Corp. for infrared (IR) imaging continuously from 690 nm to 1,300 nm, enabling optimized excitation of longer-wavelength dyes, as well as second- and third-harmonic-generation (SHG, THG) imaging. Dual simultaneous excitation wavelength configurations are also available.

An optional high-sensitivity cooled gallium arsenide phosphide (GaAsP) detector unit also enhances sensitivity and minimizes electrical noise. When combined with GaAsP detectors with high, 45% quantum efficiency, the unit provides high signal-to-noise performance. The combination of GaAsP and conventional PMTs in one system also allows users to choose either high-sensitivity detection or high-dynamic range imaging. The system is also compatible with Olypus' Scaleview objectives.

Olympus America Inc., www.olympusamerica.com