Cresset has launched forgeV10, a powerful computational suite to understand SAR and design. The software gives computational chemists control and insight into activity data enabling the planning and direction of projects. It uses the shape and electrostatic character of molecules to create qualitative and quantitative 3D models of activity that are visually stimulating and easy to communication.
The software features Cresset's ligand comparison method to align, score, and compare molecules from a biological view point. ForgeV10 is used to decipher complex SAR and communicate the results; design better molecules based on predictions which can be trusted; prepare detailed pharmacophores; virtually screen 10,000 compounds on the desktop; and generate ADME and off-target activity profiles.
Cresset Group Ltd, www.cresset-group.com