Wyatt Technology Corporation launched its new size exclusion chromatography (SEC) columns for protein analysis by multi-angle light scattering. These SEC columns are designed to achieve high resolution and reproducibility, as well as the high detection sensitivity for protein characterization.
The combined SEC-MALS method has many applications, including quantification of protein aggregation, determination of protein conjugate stoichiometry, and confirmation of the oligomeric state of a protein.
The new SEC columns cease shedding particles after a very short time, produce low light scattering baseline noise, and good pressure shock resistance. These features not only ensure high data quality and accuracy, but also improve productivity because less time is waiting for the columns to “quiet down”. Moreover, quality consistency is guaranteed as each column is individually tested by a Wyatt expert using a MALS detector before being shipped.
The columns have high resolution, reproducibility, as well as an extended for proteins classes including membrane proteins, owing to the use of high-quality silica with well-controlled surface chemistry and manufacturing processes. The columns also have a full range of pore size selections to choose from.
Wyatt Technology Corporation, www.wyatt.com