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Mass spectrometry solutions improve identification, quantitation for biological research

Tue, 06/11/2013 - 4:40pm

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AB SCIEX has unveiled three new solutions for biological researchers to improve identification and quantitation of proteins, peptides, metabolites and lipids. The company extended the applicability of SelexION technology, SWATH Acquisition and ProteinPilot software for academic research in the field of systems biology.

The launch of SelexION technology on the TripleTOF 5600+ system provides more confident identification and quantitation of molecules by delivering an additional level of separation between the liquid chromatography (LC) system and the mass spectrometer. This separation can be applied at the molecular level, the biological sub-class level or for the general removal of background interferences. The addition of SelexION technology on this high-performing accurate mass-based system with high sensitivity and high resolution extends mass spectrometry performance with differential ion mobility, which enables a new dimension of separation and selectivity.

AB SCIEX also introduced enhancements to two critical tools in proteomics workflows, including SWATH Acquisition, a technique that enables researchers to reproducibly quantify all detectable components in a single injection. Next-generation SWATH Acquisition improves data scoring, filtering and support for variable window acquisition, up to 5 times speed and scale improvement and enhanced tools for visualization and transfer of complex data sets. Also introduced was a new version of ProteinPilot software, which improves identification and quantitative results faster on larger data sets.

“We continue to evolve our innovations to broaden their usefulness with additional features and functionality that provide greater confidence in results,” says Dave Hicks, VP and GM of the Pharma and Academic Business at AB SCIEX. “The development of these expanded versions of SWATH and SelexION are the direct result of feedback we received from customers who saw the potential to apply these breakthrough technologies to a wider range of analytical challenges.”

Source: AB Sciex

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