Advertisement
Articles
Subscribe to R&D Magazine Articles
View Sample

FREE Email Newsletter

R&D Daily

Safer Drug Delivery to the Brain

February 25, 2014 1:23 pm | by Lindsay Hock, Managing Editor | Comments

Delivering drugs into the brain to treat neurological diseases and disorders has been a challenge. The current best and easiest way to get drugs anywhere in the body is to take them orally or to administer them intravenously. But the challenges for these routes of drug delivery for targets in the brain are multiple.

TOPICS:

How Laboratory Space is Changing

February 18, 2014 1:49 pm | by Bill Harris, Principal, Regional Practice Leader for Science and Technology, Perkins+Will | Comments

A generation ago, wet laboratory space would’ve included fixed casework, dense with laboratory benches, storage cabinets and equipment, but hardly any space or capacity to hold a meeting or accommodate change. Today, laboratory space design reflects an evolution in both the methods of research and the way that scientists work—individually and with their colleagues. 

TOPICS:

Why Big Data Isn’t the Big Problem for Genomic Medicine

February 14, 2014 12:07 pm | by Michael Groner, VP of engineering and chief architect, and Trevor Heritage, VP of corporate development and strategy, Appistry Inc. | Comments

Buzzwords, like a virus, spread inexorably from discipline to discipline. Take “big data,” which originated in supercomputing and now has infected finance, logistics, intelligence and defense and life science. Is there some rule requiring every presentation on genomics to include a slide comparing sequencing costs to Moore’s Law, followed by slides lamenting how much data we are producing and the resources required to act on it?

TOPICS:
Advertisement

More Hope for a HIV-1 Vaccine

February 10, 2014 9:15 am | by Lindsay Hock, Managing Editor | Comments

On the eve of the 25th World AIDS Day (December 2014), President Barack Obama expressed hope to our nation, proclaiming that an “AIDS-free generation is within our reach.” During his speech, Obama expressed how our nation has made significant strides toward strengthening scientific investments, building effective HIV/AIDS education and prevention programs and bringing together public and private stakeholders.

TOPICS:

Targeted Healing of the Immune System

February 9, 2014 10:00 am | by Lindsay Hock, Managing Editor | Comments

In the U.S. about 12,500 women are diagnosed with cervical cancer a year. Out of these women, about 4,500 progress into invasive cervical cancer or the end stage of the disease. This leaves about 8,000 women a year in the U.S. that are cured through existing standard of care treatment: surgery or chemotherapy/radiation. However, chemotherapy/radiation have terrible side effects in some cases.

TOPICS:

Trace Early, Trace Often to Improve Your Development Process

February 7, 2014 2:45 pm | by Matt Harp, Product Marketing Director, Seapine Software | Comments

Many companies have recognized an untapped opportunity for improving their development process: the requirements traceability matrix. Rather than wait until the end of the development cycle, the team builds the trace matrix when requirements first go under design control, and maintains it all the way through the submission process.

TOPICS:

Complete Containment

February 7, 2014 9:36 am | by Paul Livingstone | Hemco Corporation, AirClean Systems, Erlab, Inc., Mott Manufacturing | Comments

Laboratories are like a living organism: They need to breathe to survive. Air exchange and management is one of a laboratory’s primary functions, and like the creature that breathes with lungs, the research environment contains many cells, or pockets, of both pure and contaminated air. These enclosures protect specimens or samples from the deleterious effects of contaminated air and allow researchers to breathe freely.

TOPICS:

Can Western Blots Be Trusted?

February 6, 2014 3:26 pm | by Ning Liu, Senior Product Manager, Laboratory Separation Div., Bio-Rad Laboratories Inc., Hercules, Calif. | Comments

In an editorial cartoon that appeared in a recent issue of The Journal of Clinical Investigation, a surgeon wields a scalpel over his patient. The caption reads: “Just a little nip here and there. We don’t want it to look like it’s had any work done.” The catch? The patient is a western blot, and the doctor is presumably making his patient look presentable for publication in a peer-reviewed journal.

TOPICS:
Advertisement

How to Transform Your Lab and Business

February 6, 2014 3:15 pm | by Kim Shah, Director of Marketing and New Business Development for the Informatics, Thermo Fisher Scientific, Philadelphia, Pa. | Thermo Fisher Scientific | Comments

The biggest challenges many elite enterprises face are actually external forces completely out of their control, from geopolitical and economic macro trends to global threats to health and the environment. This lack of control creates a tumultuous global business climate that conspires to unravel even the most well-thought-out strategic plans.

TOPICS:

Cell Culture Automation: Critical for Cell Therapies and Drug Development

February 6, 2014 3:08 pm | by Kristina Klette, Don Janezic and Bobby Chavli, Hamilton Robotics, Reno, Nev. | Comments

Stem cell research has been breaking ground in new application areas over the past few years, and it’s poised for even greater growth as more companies and organizations realize the potential. In the next decade, cell-based therapies will become increasingly common for cancer, immunological disorders, cardiac failure and other conditions.

TOPICS:

Automated Strategy for Immuno-MS Sample Preparation

February 6, 2014 2:56 pm | by Brian Feild, Biotech Product Manager, Shimadzu Scientific Instruments, Columbia, Md. | Comments

Progress often requires change. For protein-based diagnostics, multiplexed assays and detection of protein isoforms will drive the adoption of a new strategy for diagnostic testing, called immuno-MS. Enzyme-linked immunosorbent assays (ELISA) have become the standard for antibody-based diagnostic tests in clinical settings. ELISAs provide specific detection of biomarkers through use of antibodies which target specific epitopes on antigens.

TOPICS:

Charting New Territory in Laboratory Automation

February 6, 2014 2:41 pm | by Dave Hickey and Connie Mardis, Siemens Healthcare Diagnostics, Tarrytown, N.Y. | Comments

Medical laboratory test results provide physicians with vital information needed for accurate diagnosis, treatment and monitoring of patients. An estimated 60 to 70% of all decisions regarding a patient’s diagnosis and treatment, hospital admission and discharge are based on laboratory test results.

TOPICS:

Lending an Automated Helping Hand

February 6, 2014 2:29 pm | by Lindsay Hock, Managing Editor | Comments

Laboratory automation techniques are commonplace, as they improve the accuracy and repeatability of laboratory operations, reduce human error in these operations and reduce cost of these operations. Defined as the use of technology to streamline or substitute manual manipulation of equipment and processes, laboratory automation offers solutions for enhancing workflows in various research laboratory environments.

TOPICS:

Optically Inclined

February 6, 2014 2:20 pm | by Paul Livingstone | Ocean Optics | Comments

Microscopy is growing at a rapid rate as the result of substantial investment in nanotechnology research. Advances in nanotechnology not only support advances in materials technology, they support developments in the semiconductor and medical devices industries. These billions of dollars drive support for advanced microscopy technologies, which are expected to become a $5 to 6 billion market globally by 2018.

TOPICS:

Automated Pre-formulation Viscosity Screening of Biological Products

February 6, 2014 1:38 pm | by Dr. Lisa Newey-Keane, Biopharmaceutical Portfolio Manager, Malvern Instruments | Comments

As interest and investment in biopharmaceuticals grows, the pressure to innovate and rapidly deliver new therapies increases. While many avenues may be pursued, the high cost of developing biological molecules increases the need to advance only those therapies with the greatest likelihood of becoming manufacturable, efficacious, safe and profitable products.

TOPICS:

Pages

X
You may login with either your assigned username or your e-mail address.
The password field is case sensitive.
Loading