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R&D Magazine's Laboratory of the Year Winners

March 23, 2014 11:30 am | Comments

The Laboratory of the Year competition, sponsored by R&D Magazine, recognizes innovative designs, materials, and construction for laboratory facilities. The winners of this prestigious competition are listed here from its start in 1967. This year marks the competition's 48th year.

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Revamping R&D: The New Laboratory In Your Pocket?

March 10, 2014 9:06 am | by Paul Denny-Gouldson, Vice President, Solution Strategy, IDBS | Comments

The nature of science shares striking similarities across many industry verticals. Whether it’s biologics, chemicals or new product formulations, they are all performed with a high degree of similarity from company to company. This is exemplified by the fact that R&D informatics platforms such as LIMS, ELNs and SDMS are used, and provide real benefits in all science-related sectors.

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Trends in Genomics Technology

March 10, 2014 8:54 am | by Barrett Bready and John Thompson, Nabsys | Comments

Ever since the study of individual genes and RNAs was first known to be important, there has been a drive to get as detailed and complete genomic information as possible. Early technologies like the hybridization-based Southern and Northern blotting methods were tremendous advances, but allowed only a handful of genomic targets to be studied at a time.

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Freudenberg Puts FEA Seal of Approval on Gasket

March 6, 2014 12:09 pm | by Nick O'Donohoe, Science and Technology Writer, Parker Group | Comments

The wind has long been used as a metaphor for constant change, wayward and capricious. Wind turbine engineers deal with that changeability every day, along with a host of other challenging factors. Their products must operate in desert sandstorms and in corrosive salt water. The ambient temperature at the turbine site can be blisteringly high or numbingly frigid.

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Storing and Tracking Samples: Preserving Contents and Managing Sample Data

March 6, 2014 11:42 am | by Kiara Biagioni, Storage Tracking Product Manager, Thermo Fisher Scientific, Waltham, Mass. | Thermo Fisher Scientific | Comments

Samples are precious resources and integral to the research process. The information derived from them is dependent on their quality, integrity and consistency. And, many samples represent a scientist’s investment in and trust of the biomedical research process. Yet, it is not unusual for samples to go missing, to find that their labels have fallen off or that they have become unusable.

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Earlier Detection of Cancer

February 28, 2014 1:55 pm | by Muneesh Tewari, Univ. of Michigan, and George Karlin-Neumann, Director of Scientific Affairs, Bio-Rad's Digital Biology Center | Comments

Finding treatments for advanced stage cancer isn’t easy. Therefore, early detection methods are paramount in the fight against the disease. Motivated by the opportunity to intervene as early as possible in the course of cancer, Dr. Muneesh Tewari, a Univ. of Michigan researcher, has been studying the diagnostic potential of blood-based biomarkers.

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Applying Unified Laboratory Intelligence in a High-Throughput, Multi-Technique Environment

February 28, 2014 11:40 am | by Michael Boruta, Industry Solutions Manager, Advanced Chemistry Development Inc. (ACD/Labs) | Comments

Gathering all analytical data from different techniques for the same sample isn’t always an easy and routine task. This problem is amplified in high-throughput environments based on sheer volume alone. Review and analysis of information can be time consuming, leading to delays in decision-making that have detrimental effects on productivity and the speed of project completion.

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Safer Drug Delivery to the Brain

February 25, 2014 1:23 pm | by Lindsay Hock, Managing Editor | Comments

Delivering drugs into the brain to treat neurological diseases and disorders has been a challenge. The current best and easiest way to get drugs anywhere in the body is to take them orally or to administer them intravenously. But the challenges for these routes of drug delivery for targets in the brain are multiple.

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How Laboratory Space is Changing

February 18, 2014 1:49 pm | by Bill Harris, Principal, Regional Practice Leader for Science and Technology, Perkins+Will | Comments

A generation ago, wet laboratory space would’ve included fixed casework, dense with laboratory benches, storage cabinets and equipment, but hardly any space or capacity to hold a meeting or accommodate change. Today, laboratory space design reflects an evolution in both the methods of research and the way that scientists work—individually and with their colleagues. 

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Why Big Data Isn’t the Big Problem for Genomic Medicine

February 14, 2014 12:07 pm | by Michael Groner, VP of engineering and chief architect, and Trevor Heritage, VP of corporate development and strategy, Appistry Inc. | Comments

Buzzwords, like a virus, spread inexorably from discipline to discipline. Take “big data,” which originated in supercomputing and now has infected finance, logistics, intelligence and defense and life science. Is there some rule requiring every presentation on genomics to include a slide comparing sequencing costs to Moore’s Law, followed by slides lamenting how much data we are producing and the resources required to act on it?

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More Hope for a HIV-1 Vaccine

February 10, 2014 9:15 am | by Lindsay Hock, Managing Editor | Comments

On the eve of the 25th World AIDS Day (December 2014), President Barack Obama expressed hope to our nation, proclaiming that an “AIDS-free generation is within our reach.” During his speech, Obama expressed how our nation has made significant strides toward strengthening scientific investments, building effective HIV/AIDS education and prevention programs and bringing together public and private stakeholders.

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Targeted Healing of the Immune System

February 9, 2014 10:00 am | by Lindsay Hock, Managing Editor | Comments

In the U.S. about 12,500 women are diagnosed with cervical cancer a year. Out of these women, about 4,500 progress into invasive cervical cancer or the end stage of the disease. This leaves about 8,000 women a year in the U.S. that are cured through existing standard of care treatment: surgery or chemotherapy/radiation. However, chemotherapy/radiation have terrible side effects in some cases.

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Trace Early, Trace Often to Improve Your Development Process

February 7, 2014 2:45 pm | by Matt Harp, Product Marketing Director, Seapine Software | Comments

Many companies have recognized an untapped opportunity for improving their development process: the requirements traceability matrix. Rather than wait until the end of the development cycle, the team builds the trace matrix when requirements first go under design control, and maintains it all the way through the submission process.

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Complete Containment

February 7, 2014 9:36 am | by Paul Livingstone | Hemco Corporation, AirClean Systems, Erlab, Inc., Mott Manufacturing | Comments

Laboratories are like a living organism: They need to breathe to survive. Air exchange and management is one of a laboratory’s primary functions, and like the creature that breathes with lungs, the research environment contains many cells, or pockets, of both pure and contaminated air. These enclosures protect specimens or samples from the deleterious effects of contaminated air and allow researchers to breathe freely.

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Can Western Blots Be Trusted?

February 6, 2014 3:26 pm | by Ning Liu, Senior Product Manager, Laboratory Separation Div., Bio-Rad Laboratories Inc., Hercules, Calif. | Comments

In an editorial cartoon that appeared in a recent issue of The Journal of Clinical Investigation, a surgeon wields a scalpel over his patient. The caption reads: “Just a little nip here and there. We don’t want it to look like it’s had any work done.” The catch? The patient is a western blot, and the doctor is presumably making his patient look presentable for publication in a peer-reviewed journal.

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