After another year of flat spending in 2013, global investment in R&D is forecast to grow by 3.8% to $1.6 trillion in 2014, according the annual R&D Magazine Global Funding Forecast. In the U.S., federal spending is forecast to increase modestly (1.5%), another promising sign, but it’s fair to say the pressure is still on to do more with less, particularly in Big Pharma where recent R&D cuts have been the most dramatic.
Pharmaceutical companies are constantly seeking ways to improve efficiency in order to increase productivity, all while speeding up innovation and protecting intellectual property (IP). The use of mobile applications (apps) in the laboratory has been investigated as a means to achieve these goals. By allowing scientists to move freely around the laboratory, mobile apps add value to suboptimal processes requiring non-value-added steps.
High-speed rail is a frequently discussed topic, but one that has yet to become a reality in the U.S. A number of states and regions in the U.S. including Texas, California, the Pacific Northwest and Minnesota, to name a few, have planned projects to bring high-speed rail to fruition.
If a senior engineer left an organization suddenly, how many hours would it take for the engineering team to take over his projects, confident that they understand not only the designs, but why those designs are the way they are? The typical answer is “far too many”. Widespread use of CAE and data management tools have made this task much easier than before, but these tools do little to record the thinking behind the results.
Fluorescent proteins have helped researchers open doors to countless molecular imaging applications and deepened our understanding of biological processes. Without fluorescence, advancements in oncology, drug discovery and any field that requires single-cell to whole-body imaging would be substantially limited.
Rechargeable lithium-ion batteries are key components for portable electronics, medical devices, industrial equipment and automobiles. They are light weight, provide high energy density and recharge without memory effects. Much research has been spent on improving product safety, lifecycle and power output over a range of high and low temperatures, yet understanding fundamental processes and degradation mechanism remains a challenge.
All types of research laboratories rely on a set of core utilities to enable and support work functions. These are often overlooked as a commodity called “consumables”, but in reality they are indispensable nutrients that vary greatly in quality and reliability. Just as a human can’t exist without water, oxygen and food, the research facility cannot make do without water, gas, air, lighting and, increasingly, high-throughput data.
Spectroscopy is an analytical technique used to identify and determine the physical characteristics of materials through the measurement of emissions and absorption of electromagnetic spectra. A staple in any research laboratory, the technique makes its main home in pharmaceutical, biotechnology and chemical laboratories.
In today’s fast-paced markets, engineers are continuously challenged to deliver products that meet market demand, improve operational efficiency and exceed customer expectations. Multiphysics simulation is an essential component of the product design workflow for creating innovative designs, especially when building prototypes becomes impractical or when taking actual measurements is not possible.
When considering potential drug delivery vehicles, liposomes are an important option and have already been approved for use with a number of therapeutic formulations. Liposomes are comprised of phospholipids and may be single- or multi-layered, can be produced in different sizes and have a hydrophilic interior and hydrophobic shell. They are biodegradable, non-toxic and capable of encapsulating both hydrophilic and hydrophobic materials.
Thirty years have passed since 3-D printers first appeared, but only recently have they hinted at a new era of manufacturing. The first working 3-D printer was created in 1984 by Chuck Hull of 3D Systems Corp. This early device, based on stereolithography, gave way to the first truly practical 3-D printing, or “3DP”, technology patented by the Massachusetts Institute of Technology in 1993.
Few areas of instrumentation have prompted as much development or efforts toward innovation as spectroscopy. Without sophisticated approaches to handling light, spectrometers as we know them would not function, and we would be without a deep understanding of the chemical nature of the world around us.
Driven by rapid growth in forensics, biotechnology, disease diagnostics and environmental regulations, chromatography systems have become a laboratory staple. Used for the separation of complex mixtures, detection of illicit drugs and the production of pharmaceuticals, the biotechnology and pharmaceutical industries are the prime users of chromatography techniques.
The unique properties of engineered nanoparticles have created intense interest in their environmental behavior. Due to the increased use of nanotechnology in consumer products, industrial applications and health care technology, nanoparticles are more likely to enter the environment. For this reason, it’s not only important to know the type, size and distribution of nanoparticles, but it’s also crucial to understand their impact.
The stakes are incredibly high for the safety and compliance efforts of today’s oil and gas industry. Engineers and crews must be trained for increasingly complex processes and procedures used aboard drilling rigs and production platforms. The consequences of inadequate training during oil production can be disastrous to both operator crews and the environment.