There’s a new “gold standard” in the sensitivity of weighing scales. Using the same technology with which they created the world’s first fully functional nanotube radio, researchers at Lawrence Berkeley National Laboratory have fashioned a nanoelectromechanical system (NEMS) that can function as a scale sensitive enough to measure the mass of a single atom of gold.
Alex Zettl, a physicist at Berkeley Lab's Materials Sciences Division (MSD) and UC Berkeley’s Physics Department, where he is the director of the Center of Integrated Nanomechanical Systems, led this research. Working with him were members of his research group, Kenneth Jensen and Kwanpyo Kim.
“For the past 15 years or so, the holy grail of NEMS has been to push them to a small enough size with high enough sensitivity so that they might resolve the mass of a single molecule or even single atom,” says Alex Zettl, a physicist at Berkeley who led the research. “This has been a challenge even at cryogenic temperatures where reduced thermal noise improves the sensitivity. We have achieved sub-single-atom resolution at room temperature!”
The new NEMS mass sensor consists of a single carbon nanotube (CNT) that is double-walled to provide uniform electrical properties and increased rigidity. One tip of the CNT is free and the other tip is anchored to an electrode in close proximity to a counter-electrode. A DC voltage source, such as from a battery or a solar cell array, is connected to the electrodes. Applying a DC bias creates a negative electrical charge on the free tip of the nanotube. An additional radio frequency wave "tickles" the nanotube, causing it to vibrate at a characteristic “flexural” resonance frequency.
When an atom or molecule is deposited onto the CNT, the tube’s resonant frequency changes in proportion to the mass of the atom or molecule, much like the added mass of a diver changes the flexural resonance frequency of a diving board. Measuring this change in frequency reveals the mass of the impinging atom or molecule.
Using their NEMS mass sensor, Zettl and his team were able to weigh individual gold atoms and measure masses as small as two fifths that of a gold atom at room temperature and in just a little more than 1 sec. A gold atom has a mass of 3.25 x 10-25 kg.
While there have been other NEMS that function as mass sensors before, most of these previous devices were fashioned from silicon, and none had achieved the magical single-atom resolution at room temperature. The CNT mass sensor of Zettl’s group is a thousand times smaller by volume than typical NEMS.
While scientists already have the ability to measure the mass of individual atoms through mass spectrometry, this new CNT NEMS mass sensor offers some distinct advantages and opens the door to new possibilities, Kenneth Jensen, another researcher on the project, explains.
“Unlike mass spectrometry, our device does not require the ionization of neutral atoms or molecules that can destroy samples such as proteins. Also unlike mass spectrometers, our carbon nanotube mass sensor becomes more sensitive at higher mass ranges, which makes it more suitable for measuring large biomolecules like DNA. Finally, our device is small enough so that, in time, it could be incorporated onto a chip.”
To view the paper “An Atomic-resolution Nanomechanical Mass Sensor” in Nature Nanotechnology click here
