The human brain is capable of a neural workaround that compensates for the buildup of beta-amyloid, a destructive protein associated with Alzheimer’s disease, according to a new study led by Univ. of California, Berkeley researchers. The findings could help explain how some older adults with beta-amyloid deposits in their brain retain normal cognitive function while others develop dementia.
Gilead Sciences has reached a deal with several generic drugmakers to produce a cheaper version of its popular, $1,000-per-pill hepatitis C drug Sovaldi for use in developing countries. Gilead said that the India-based companies will make a generic version of Sovaldi, also known as sofosbuvir, and another investigational drug for distribution in 91 countries.
Self-injury is one of the most difficult behaviors associated with autism and other developmental or intellectual disabilities, and a private facility outside Boston that takes on some of the hardest-to-treat cases is embroiled in a major debate: Should it use electrical skin shocks to try to keep patients from harming themselves or others?
Researchers have developed an optical method that makes individual proteins, such as the proteins characteristic of some cancers, visible. Other methods that achieve this only work if the target biomolecules have first been labeled with fluorescent tags, but this approach is very difficult. By contrast, the new method allows scientists to directly detect the scattered light of individual proteins via their shadows.
Sugar is a vital source of energy. Understanding just how sugar makes its way into the cell could lead to the design of better drugs for diabetes patients and an increase in the amount of fruits and vegetables farmers are able to grow. Stanford Univ. researchers have recently uncovered one of these "pathways” into the cell by piecing together proteins slightly wider than the diameter of a strand of spider silk.
Two massive, 20,000-lb buoys decked out with the latest in meteorological and oceanographic equipment will enable more accurate predictions of the power-producing potential of winds that blow off U.S. shores. The bright yellow buoys are being commissioned by the Pacific Northwest National Laboratory in Washington state's Sequim Bay.
Things can go downhill fast when a patient has sepsis, a life-threatening condition in which bacteria or fungi multiply in a patient's blood—often too fast for antibiotics to help. A new device inspired by the human spleen and developed by a team at Harvard's Wyss Institute for Biologically Inspired Engineering may radically transform the way doctors treat sepsis.
Lamprey—slimy, eel-like parasitic fish with tooth-riddled, jawless sucking mouths—are rather disgusting to look at, but thanks to their important position on the vertebrate family tree, they can offer important insights about the evolutionary history of our own brain development, a recent study suggests.
The very idea of fibers made of carbon nanotubes is neat, but Rice Univ. scientists are making them neat—literally. The single-walled carbon nanotubes in new fibers created at Rice line up like a fistful of uncooked spaghetti through a process designed by chemist Angel Martí and his colleagues.
The central mystery of quantum mechanics is that small chunks of matter sometimes seem to behave like particles, sometimes like waves. For most of the past century, the prevailing explanation of this conundrum has been what’s called the “Copenhagen interpretation”—which holds that, in some sense, a single particle really is a wave, smeared out across the universe, that collapses into a determinate location only when observed.
As integrated circuits become increasingly miniaturized and the sizes of magnetic components approach nanoscale dimensions, magnetic properties can disappear. Scientists in Japan, with the help of a form of electron microscopy called split-illumination electron holography, have gained important insights into the development of stable, strong nanomagnets by discovering magnetism-amplifying atomic disorder in iron-aluminum alloys.
The central mystery of quantum mechanics is that small chunks of matter sometimes seem to behave like particles, sometimes like waves. The traditional view holds that a single particle really is a wave that collapses only when observed. But John Bush, of the Massachusetts Institute of Technology, believes that another explanation, the pilot-wave theory, deserves a second look.
Evolutionary biology techniques can and must be used to help solve global challenges in agriculture, medicine and environmental sciences, advises a nine-member global team led by an evolutionary ecologist from Univ. of California, Davis.
A habitual party crasher, Apple has a history of arriving late and making a big splash in various gadget categories. But can it continue with the Apple Watch? Smartwatches have been around for a few years, but makers such as Samsung and Sony have failed to make them a runaway hit. Apple's Watch won't go on sale until early 2015 and raises questions: Can the company work its magic as it has in the past?
Scientists at NIST have determined that polonium-209, the longest-lived isotope of this radioactive heavy element, has a half-life about 25% longer than the previously determined value, which had been in use for decades. The new NIST measurements could affect geophysical studies such as the dating of sediment samples from ocean and lake floors.