The RIKEN Omics Science Center (OSC) has partnered with American company Complete Genomics to develop next-generation technology for the rapid analysis of individual-level human gene expression.
The partnership combines the OSC’s expertise in omics science with technology for the rapid sequencing of complete human genomes developed by Complete Genomics to explore new possibilities in the study and application of cutting-edge gene expression analysis.
Collaborative research in the new project will seek to clarify the underlying mechanisms of complex gene expression in humans. To do so, complete genomes of a number of individuals, sequenced by Complete Genomics, will be analyzed for differences in genetic information and RNA expression using RIKEN’s CAGE (cap analysis of gene expression) technology. While technology for the analysis of complete human genomes is today increasingly widespread, the current collaboration takes such sequencing one step further, focusing on RNA levels (transcriptome) representative of detailed differences in gene arrangement, with important applications to genetic profiling.
In the future, through collaborative research using technology developed independently by the two organizations, RIKEN and Complete Genomics envision further cooperation toward the creation of a commissioned genome analysis service. The first stage of the new partnership was launched on 7 January 2010.
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