2010 R&D 100 Winner
The Kinetex Core-Shell Technology HPLC Columns from Phenomenex, Inc., Torrance, Calif., makes it possible for labs to achieve ultra-high efficiencies on conventional liquid chromatography (LC) systems and high performance liquid chromatography (UHPLC) systems. The result: lower levels of detection and quantitation, the identification of more impurities, higher throughput and lab productivity, and increased solvent savings.
The columns are available with 1.7 µm and 2.6 µm core-shell HPLC particles. The 1.7 μm particles have a 0.23 μm porous shell and a 1.25 μm solid core. The 2.6 μm particles have a 0.35 μm porous shell and a 1.9 μm solid core.
Kinetex core-shell particles are not fully porous like 3 µm and 5 µm particles packed in most of the columns used today. The core-shell particles are engineered to have a near perfect particle size distribution and uniform particle morphology. The design results in efficiencies on the 2.6 µm Kinetex particle that are comparable to sub-2 µm fully porous particles.
Technology
HPLC column ultra-high efficiency core-shell particle media
Developer
Phenomenex, Inc.
Development Team
The Kinetex Core-Shell Technology HPLC Columns Development Team frm Phenomenex:
Jeremy Bierman
Mike Chitty
