2009 R&D 100 Winner
The Reveleris system from W. R. Grace & Co.-Conn., Columbia, Md., streamlines the purification of compounds for pharmaceutical and agricultural applications. The system departs from current flash chromatography technology by combining traditional ultraviolet (UV) detection with evaporative light scattering detection (ELSD) to detect compounds that would have been missed by UV alone. The RevealX technology simultaneously processes multiple detector signals and generates information about sample composition, purity, and mass; competitive systems require additional steps. It identifies impurities and target compounds other systems miss thanks to the combined UV and ELSD detection. The Reveleris system surmounts the challenges of splitting fluidics and signal integration in a system that meets the space, safety, and ergonomic constraints of today’s labs. The fully-integrated instrument provides the chemist with quantitative and qualitative information that was previously impossible to obtain on a single system in a single experiment.
Technology
Compound purification system
Developer
W. R. Grace & Co.-Conn
