Wednesday, September 24, 2008
2008 R&D 100 Winner
Academic researchers and biopharmaceutical companies are demanding lower-cost, high-quality oligonucleotides for various experimental technologies. Oligonucleotide manufacturers simply cannot satisfy the market’s needs without a new automated purification technology to complement their oligonucleotide synthesis platforms. Enter the Clarity QSP from Phenomenex, Inc., Torrance, Calif., a solid-phase extraction (SPE) chromatography product that provides a quick and simple alternative to conventional reversed-phase mechanisms for purifying synthetic oligonucleotides. Clarity QSP’s technology offers improved performance over these traditional methods which are limited by low purities and yields, consume large solvent volumes, and employ toxic ion-pairing reagents. By comparison, Clarity QSP delivers purities ranging from 90% to 95% and recovery values of 90% or higher, while simplifying the process by employing fewer buffers and wash steps. When used in conjunction with standard parallel processing automation equipment, Clarity QSP provides a rapid, simple, and cost-effective means of purifying large quantities of synthetic oligonucleotides.
Technology
Solid-phase extraction chromatography product
Developer
Phenomenex, Inc.
