The number of American men and women with big-bellied, apple-shaped figures—the most dangerous kind of obesity—has climbed at a startling rate over the past decade, according to a government study. People whose fat has settled mostly around their waistlines instead of in their hips, thighs, buttocks or all over are known to run a higher risk of heart disease, diabetes and other obesity-related ailments.
Yale Univ. scientists are exploring uncharted genomic islands to study new chemistry between bacteria and their hosts, from invertebrates to humans. One such discovery is published in Chemistry & Biology. The findings describe a biological pathway that contains a hypothetical protein responsible for the formation of a rare, bicyclic sugar.
The American strategy on Ebola is two-pronged: step up desperately needed aid to West Africa and, in an unusual step, train U.S. doctors and nurses for volunteer duty in the outbreak zone. At home, the goal is to speed up medical research and put hospitals on alert should an infected traveler arrive.
Deploying sophisticated high-throughput sequencing technology, a team of Whitehead Institute and Broad Institute researchers have collaborated on a comprehensive, high-resolution mapping that confirms a post-transcriptional RNA modification called pseudouridylation does indeed occur naturally in messenger RNA. This is somewhat surprising finding using a new quantitative sequencing method.
An interdisciplinary development team that includes Lockheed Martin, the Air Force Research Laboratory and the Univ. of Notre Dame has demonstrated the airworthiness of a new beam control turret being developed for DARPA to give 360-degree coverage for high-energy laser weapons operating on military aircraft. An aircraft equipped with the laser has already conducted eight test flights in Michigan.
Researchers from North Carolina State Univ. have developed a technique for controlling the surface tension of liquid metals by applying very low voltages, opening the door to a new generation of reconfigurable electronic circuits, antennas and other technologies. The technique hinges on the fact that the oxide “skin” of the metal acts as a surfactant, lowering the surface tension between the metal and the surrounding fluid.
The miVac Quattro from Genevac is a sample concentrator for biological laboratories tasked with handling larger numbers of samples. The miVac Quattro centrifugal vacuum concentrator removes a wide range of solvents, suiting it for concentrating samples in applications including oligonucleotide synthesis, RNA/DNA preparation and peptide preparation.
The Development Microlute from Porvair Sciences is a solid phase extraction (SPE) microplate which provides an assortment of phase chemistries and sorbent loadings in a single plate, suiting it for method development.
Building on previous animal and human research, a new study has identified an electrophysiological marker for threat in the brain. The findings illustrate how fear arises in the brain when individuals are exposed to threatening images, and the study is the first to separate emotion from threat by controlling for the dimension of arousal, the emotional reaction provoked, whether positive or negative, in response to stimuli.
Heat drives classical phase transitions, but much stranger things can happen when the temperature drops. If phase transitions occur at the coldest temperatures imaginable, where quantum mechanics reigns, subtle fluctuations can dramatically transform a material. Scientists have explored this frigid landscape of absolute zero to isolate and probe these quantum phase transitions with unprecedented precision.
At one o'clock in the morning, layers of warm plastic are deposited on the platform of the 3-D printer that sits on scientist Rebecca Erikson's desk. A small plastic housing, designed to fit over the end of a cell phone, begins to take shape. Pulling it from the printer, Erikson quickly pops in a tiny glass bead and checks the magnification.
The fastest land animal on Earth, the cheetah, is able to accelerate to 60 mph in just a few seconds. As it ramps up to top speed, a cheetah pumps its legs in tandem, bounding until it reaches a full gallop. Now, researchers have developed an algorithm for bounding that they’ve successfully implemented in a fully functional robotic cheetah.
Conditions on Earth for the first 500 million years after it formed may have been surprisingly similar to the present day, complete with oceans, continents and active crustal plates. This alternate view of Earth’s first geologic eon, called the Hadean, has gained substantial new support from the first detailed comparison of zircon crystals that formed more than 4 billion years ago with those formed contemporaneously in Iceland.
A potential way to treat muscular dystrophy directly targets muscle repair instead of the underlying genetic defect that usually leads to the disease. Muscular dystrophies are a group of muscle diseases characterized by skeletal muscle wasting and weakness. Mutations in certain proteins, most commonly the protein dystrophin, cause muscular dystrophy in humans and also in mice.
The quest to create artificial “squid skin”—camouflaging metamaterials that can “see” colors and automatically blend into the background—is one step closer to reality, thanks to a breakthrough color-display technology unveiled by Rice Univ. The new full-color display technology uses aluminum nanoparticles to create the vivid red, blue and green hues found in today’s top-of-the-line LCD televisions and monitors.