Researchers have long sought alternatives to morphine that curb its side effects, including dependency, nausea and dizziness. Now, an experiment at SLAC National Accelerator Laboratory has supplied the most complete atomic-scale map of such a compound docked with a cellular receptor that regulates the body’s pain response and tolerance.
While genomics is the study of all of the genes in a cell or organism, epigenomics is the study of all the genomic add-ons and changes that influence gene expression but aren’t encoded in the DNA sequence. A variety of new epigenomic information is now available in a collection of studies published in Nature by the National Institutes of Health Roadmap Epigenomics Program.
Researchers at the Univ. of Illinois at Urbana-Champaign have developed a unique single-step process to achieve 3-D texturing of graphene and graphite. Using a commercially available thermally activated shape-memory polymer substrate, this 3-D texturing, or "crumpling," allows for increased surface area and opens the doors to expanded capabilities for electronics and biomaterials.
When oil from the Deepwater Horizon spill first began washing ashore on Pensacola Municipal Beach in June 2010, populations of sensitive microorganisms, including those that capture sunlight or fix nitrogen from the air, began to decline. At the same time, organisms able to digest light components of the oil began to multiply, starting the process of converting the pollutant to carbon dioxide and biomass.
Computer chips’ clocks have stopped getting faster. To keep delivering performance improvements, chipmakers are instead giving chips more processing units, or cores, which can execute computations in parallel. But the ways in which a chip carves up computations can make a big difference to performance.
Frequency combs are the rulers of light. By counting a wavelength's many oscillations, they measure distance and time with extraordinary precision and speed. Since the discovery of optical frequency combs in the 1990s, many applications in metrology, spectroscopy and frequency synthesis have emerged.
VICI Valco’s Cheminert High-Pressure PEEK Fittings are rated at 5,000 psi with fingertight nuts, well beyond the burst strength of most PEEK tubing. The taper angle and detail design conform to the industry standard established by the Valco line. The Cheminert UHPLC Fitting designs permit direct connection of 360-µm OD fused silica, PEEK, stainless or electroformed nickel tubing without having to use troublesome liners.
When electronic states in materials are excited during dynamic processes, interesting phenomena such as electrical charge transfer can take place on quadrillionth-of-a-second, or femtosecond, timescales. Numerical simulations in real time provide the best way to study these processes, but such simulations can be extremely expensive.
The depth and efficiency of the U.S. natural gas market would buffer it against potential local policy interventions aimed at limiting access to shale gas resources, according to a new paper by energy economists at Rice Univ.’s Baker Institute for Public Policy.
Personal or philosophical opposition to vaccines would not be an authorized exemption for the parents of school-age children under a measure that received a public hearing before a House committee on Tuesday, drawing at least two dozen opponents to the proposed change.
Univ. of Wisconsin-Madison geoscientists and engineers are working with industry partners and the U.S. Dept. of Energy to develop a highly detailed monitoring system for geothermal wells. Man-made geothermal systems that emulate natural ones could, by some conservative estimates, produce a total of 100 gigawatts of cost-competitive electricity over the next 50 years.
A group of astronomers from the U.S., Europe, Chile and South Africa have determined that 70,000 years ago a recently discovered dim star is likely to have passed through the solar system's distant cloud of comets, the Oort Cloud. No other star is known to have ever approached our solar system this close—five times closer than the current closest star, Proxima Centauri.
At least five mass extinction events have profoundly changed the history of life on Earth. But a new study led by researchers at the Univ. of Gothenburg shows that plants have been very resilient to those events. For over 400 million years, plants have played an essential role in almost all terrestrial environments and covered most of the world's surface.
A team of researchers from the Univ. of Michigan and Western Michigan Univ. is exploring new materials that could yield higher computational speeds and lower power consumption, even in harsh environments. Most modern electronic circuitry relies on controlling electronic charge within a circuit, but this control can easily be disrupted in the presence of radiation, interrupting information processing.
Compact, sensitive and fast nanodetectors are considered to be somewhat of a "Holy Grail" sought by many researchers around the world. And now a team of scientists in Italy and France has been inspired by nanomaterials and has created a novel solid-state technology platform that opens the door to the use of terahertz photonics in a wide range of applications.