Customized genome editing has major potential for application in medicine, biotechnology, food and agriculture. Now, in a paper published in Molecular Cell, North Carolina State Univ. researchers and colleagues examine six key molecular elements that help drive this genome editing system, which is known as CRISPR-Cas.
The federal government is closing a gap in Ebola screening at airports while states from New York to Texas to California work to get hospitals and nurses ready in case another patient turns up somewhere in the U.S. with the deadly disease. Under the rule going into effect Wednesday, air travelers from the West African nations must enter the U.S. through one of five airports doing special screenings and fever checks for Ebola.
Researchers at the Univ. of Pennsylvania and The Children's Hospital of Philadelphia have used graphene to fabricate a new type of microelectrode that solves a major problem for investigators looking to understand the intricate circuitry of the brain. The see-through, one-atom-thick electrodes can obtain both high-resolution optical images and electrophysiological data for the first time.
Researchers from North Carolina State Univ. have developed new software that estimates how much farther electric vehicles can drive before needing to recharge. The new technique requires drivers to plug in their destination and automatically pulls in data on a host of variables to predict energy use for the vehicle.
Massive black holes spewing out radio frequency-emitting particles at near-light speed can block formation of new stars in aging galaxies, a study has found. The research provides crucial new evidence that it is these jets of radio frequency feedback streaming from mature galaxies’ central black holes that prevent hot free gas from cooling and collapsing into baby stars.
Scientists think of CD8 T cells as long-lived cells that become tuned to fight just one pathogen, but a new study finds that once CD8 T cells fight one pathogen, they also join the body’s “innate” immune system, ready to answer the calls of the cytokine signals that are set off by a wide variety of infections.
Thermo Fisher Scientific has introduced the Thermo Scientific Q Exactive Focus LC-MS/MS, a high-resolution accurate-mass (HRAM) Orbitrap mass spectrometer. The Q Exactive Focus benchtop LC-MS/MS combines high-performance quadrupole precursor ion selection with an HRAM Orbitrap mass analyzer, providing excellent mass accuracy, sensitivity and fast polarity switching.
Bio-Rad Laboratories Inc. has introduced the PrimePCR Assays for Droplet Digital PCR (ddPCR). The release expands Bio-Rad’s current offering of pre-designed and fully wet-laboratory validated assays by an additional 100 assays for copy number variation (CNV) and 92 assays for mutation detection. Bio-Rad will also be adding 5,620 mutation detection assays that were created using the same algorithms and design rules as the wet-laboratory validated assays.
Laser physicists in Australia have built a tractor beam that can repel and attract objects, using a hollow laser beam that is bright around the edges and dark in its center. It is the first long-distance optical tractor beam and has moved particles one-fifth of a millimeter in diameter a distance of up to 20 cm, around 100 times further than previous experiments.
Research by an international team of scientists has uncovered a new, unpredicted behavior in a copper oxide material that becomes superconducting at relatively high temperatures. This new phenomenon presents a challenge to scientists seeking to understand its origin and connection with high-temperature superconductivity. Their ultimate goal is to design a superconducting material that works at room temperature.
Joint Quantum Institute scientists have been developing a model for what happens when ultracold atomic spins are trapped in an optical lattice structure with a “double-valley” feature, where the repeating unit resembles the letter “W”. This new theory result opens up a novel path for generating what’s known as the spin Hall effect, an important example of spin-transport.
New medications created by pharmaceutical companies have helped millions of Americans alleviate pain and suffering from their medical conditions. However, the drug creation process often misses many side effects that kill at least 100,000 patients a year, according to Nature.
The large amount of jet fuel required to fly an airplane from point A to point B can have negative impacts on the environment and a traveler's wallet. With funding from NASA and the Boeing Company, engineers from Caltech and the Univ. of Arizona have developed a device that lets planes fly with much smaller tails, reducing the planes' overall size and weight, thus increasing fuel efficiency.
In a design that mimics a hard-to-duplicate texture of starfish shells, Univ. of Michigan engineers have made rounded crystals that have no facets. The team calls the crystals "nanolobes". The nanolobes' shape and the way they're made have promising applications. The geometry could potentially be useful to guide light in advanced LEDs, solar cells and non-reflective surfaces.
Rice Univ. bioengineers have found new evidence of a possible link between diabetes and the hardening of heart valves. A Rice laboratory, in collaboration with the Univ. of Texas Health Science Center at Houston Medical School, discovered that the interstitial cells that turn raw materials into heart valves need just the right amount of nutrients for proper metabolic function.