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At the interface of math and science

September 30, 2014 8:09 am | by Julie Cohen, UC Santa Barbara | News | Comments

Univ. of California, Santa Barbara’s Paul Atzberger, a professor in the Department of Mathematics and in mechanical engineering, often works in areas where mathematics plays an ever more important role in the discovery and development of new ideas. Most recently he has developed new mathematical approaches to gain insights into how proteins move around within lipid bilayer membranes.

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Automated sorting through metagenomes

September 30, 2014 8:05 am | by Lynn Yarris, Lawrence Berkeley National Laboratory | News | Comments

Microbes have an amazing ability to feed on plant biomass and convert it into other chemical products. Tapping into this talent has the potential to revolutionize energy, medicine, environmental remediation and many other fields. The success of this effort hinges in part on metagenomics, the emerging technology that enables researchers to read all the individual genomes of a sample microbial community at once.

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Researchers develop transparent nanoscintillators for radiation detection

September 30, 2014 7:56 am | by Traci Peterson, Univ. of Texas at Arlington | News | Comments

A Univ. of Texas at Arlington research team says recently identified radiation detection properties of a light-emitting nanostructure built in their lab could open doors for homeland security and medical advances. In a paper to be published in Optics Letters, the team describes a new method to fabricate transparent nanoscintillators by heating nanoparticles composed of lanthanum, yttrium and oxygen until a transparent ceramic is formed.

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Fat molecules influence form, function of key photosynthesis protein

September 30, 2014 7:48 am | by Elizabeth K. Gardner, Purdue Univ. | News | Comments

A mysterious space within a protein critical to photosynthesis is filled with fat molecules that influence both the protein’s architecture and electrical properties, according to two recent studies. Researchers studied the atomic structure of, and electrical interactions within, the cytochrome bf complex, a protein complex central to the transport of electrons within membranes of a plant cell, a critical step in photosynthesis.

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High-speed drug screen

September 30, 2014 7:37 am | by Anne Trafton, MIT News Office | News | Comments

Massachusetts Institute of Technology engineers have devised a way to rapidly test hundreds of different drug-delivery vehicles in living animals, making it easier to discover promising new ways to deliver a class of drugs called biologics, which includes antibodies, peptides, RNA and DNA, to human patients.

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2nd Annual Pharma Data Analytics Conference

September 29, 2014 3:10 pm | Events

The 2nd Annual Pharma Data Analytics Conference will enable senior-level analytics professionals to improve the bottom line of their business through utilizing the potential of big data. Driven by single-track case study presentations from Pfizer, Celgene, Novartis, Merck and many others, this program will explore recent trends in the pharmaceutical environment, including the influence of analytics in the commercial space, data visualization tools and techniques and methodologies for forecasting across multiple business units.

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Surface Enhanced Raman Spectroscopy Substrate

September 29, 2014 1:33 pm | Product Releases | Comments

Ocean Optics has introduced a new substrate for surface enhanced Raman spectroscopy (SERS) applications. Using precisely controlled gold nanoparticles, Ocean Optics SERS substrates amplify very weak Raman signals by many orders of magnitude. The result is fast, repeatable SERS measurements for the identification and quantification of SERS-active analytes.

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Portable Indoor Air Quality Monitor

September 29, 2014 1:14 pm | Product Releases | Comments

The new AQ Expert from E Instruments International provides monitoring and real-time data logging for indoor air quality testing in a variety of settings, including laboratories and cleanrooms. The AQ Expert includes up to 11 parameters and detects a wide variety of gases and atmospheric characteristics.

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Scientists identify the signature of aging in the brain

September 29, 2014 12:58 pm | News | Comments

How the brain ages is still largely an open question because this organ is mostly insulated from direct contact with other systems in the body. In recent research, scientists in Israel found evidence of a unique “signature” that may be the “missing link” between cognitive decline and aging. The scientists believe that this discovery may lead, in the future, to treatments that can slow or reverse cognitive decline in older people.

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Scientists make droplets move on their own

September 29, 2014 12:51 pm | Videos | Comments

Droplets are simple spheres of fluid, not normally considered capable of doing anything on their own. But now researchers have made droplets of alcohol move through water, even moving through complex mazes. The droplets can be led to certain targets, using a surprisingly simple impetus. In the future, such moving droplets may deliver medicines, moving entire chemistries to targets.

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Scientists improve microscopic batteries with homebuilt imaging analysis

September 29, 2014 12:26 pm | News | Comments

In a rare case of having their cake and eating it too, scientists from NIST and other institutions have developed a toolset that allows them to explore the complex interior of tiny, multi-layered batteries they devised. It provides insight into the batteries’ performance without destroying them, which results in both a useful probe for scientists and a potential power source for micromachines.

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Biologists find early sign of cancer

September 29, 2014 11:10 am | by Anne Trafton, MIT News Office | News | Comments

Years before they show any other signs of disease, pancreatic cancer patients have very high levels of certain amino acids in their bloodstream, according to a new study. This finding, which suggests that muscle tissue is broken down in the disease’s earliest stages, could offer new insights into developing early diagnostics for pancreatic cancer, which kills about 40,000 Americans every year.

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Simulations reveal an unusual death for ancient stars

September 29, 2014 11:01 am | by Linda Vu, Lawrence Berkeley National Laboratory | News | Comments

Certain primordial stars—those between 55,000 and 56,000 times the mass of our sun, or solar masses—may have died unusually. In death, these objects—among the universe’s first-generation of stars—would have exploded as supernovae and burned completely, leaving no remnant black hole behind.

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Tech-friendly cities struggle with new biz rules

September 29, 2014 9:12 am | by Philip Marcelo, Associated Press | News | Comments

A renowned technology hub that is home to some of the country's top universities, Boston is emerging as an unlikely battleground for web-based businesses like Airbnb and Uber, with some saying more regulations are needed to prevent the upstarts from disrupting more established industries. Cities like Boston have been wrestling with the same questions and developing solutions ranging from outright bans to minimum safety requirements.

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Unlocking enzyme synthesis of rare sugars to create drugs with fewer side effects

September 29, 2014 8:57 am | by Katie Bethea, Oak Ridge National Laboratory | News | Comments

An Oak Ridge National Laboratory team has unlocked the enzymatic synthesis process of rare sugars, which are useful in developing drugs with low side effects. In a recently published paper, the team reported the pioneering use of neutron and x-ray crystallography and HPC to study how the enzyme D-xylose isomerase, or XI, can cause a biochemical reaction in natural sugar to produce rare sugars.

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